cefotaxime
TL;DR: cefotaxime (CAS 64485-93-4) is a chemical compound with molecular formula C16H17N5O7S2 and molecular weight 455.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6R,7R)-3-(acetyloxymethyl)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Also Known As: cefotaxime, Claforan, Anticefotaxime, Cephotaxime, Cefotaxime acid
| Molecular Formula | C16H17N5O7S2 |
|---|---|
| Molecular Weight | 455.06 g/mol |
| LogP | -0.6225 |
| Topological Polar Surface Area | 173.51 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 7 |
| Exact Mass | 455.05695 |
| Heavy Atoms | 30 |
| Complexity | 972.9401 |
Chemical Identifiers
| CAS Number | 64485-93-4 |
|---|---|
| SMILES | CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N/OC)/C3=CSC(=N3)N)SC1)C(=O)O |
Product Overview
cefotaxime (CAS 64485-93-4), with molecular formula C16H17N5O7S2 and molecular weight 455.06 g/mol. IUPAC: (6R,7R)-3-(acetyloxymethyl)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.
Chemical Property Profile of cefotaxime
Property Insights of cefotaxime
The XLogP value of -0.6225 indicates that cefotaxime is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 173.51 Ų indicates high polarity, suggesting cefotaxime may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, cefotaxime has 3 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of cefotaxime?
The CAS number of cefotaxime is 64485-93-4.
What is the molecular formula of cefotaxime?
The molecular formula of cefotaxime is C16H17N5O7S2.
What is the molecular weight of cefotaxime?
The molecular weight of cefotaxime is 455.06 g/mol.
Where can I buy cefotaxime?
You can request a quote for cefotaxime directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for cefotaxime?
Yes, KEHONG BIO provides custom synthesis services for cefotaxime and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.