Vinblastine-N-methyl amide sulfate
TL;DR: Vinblastine-N-methyl amide sulfate (CAS 64448-88-0) is a chemical compound with molecular formula C46H61N5O12S and molecular weight 907.40 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl 13-[11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-8-methyl-10-(methylcarbamoyl)-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraene-13-carboxylate;sulfuric acid
Also Known As: Chromium nicotinate, Vinblastine-N-methyl amide sulfate, Vincaleukoblastine N-methylamide sulfate (salt), Vincaleukoblastine, 3-de(methoxycarbonyl)-3-((methylamino)carbonyl)-, sulfate (1:1) salt, Vincaleukoblastine, 3-de(methoxycarbonyl)-3-[(methylamino)carbonyl]-, sulfate (1:1) (salt)
| Molecular Formula | C46H61N5O12S |
|---|---|
| Molecular Weight | 907.40 g/mol |
| LogP | 2.9111 |
| Topological Polar Surface Area | 231.5 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 13 |
| Rotatable Bonds | 7 |
| Exact Mass | 907.40375 |
| Heavy Atoms | 64 |
| Complexity | 2505.7095 |
Chemical Identifiers
| CAS Number | 64448-88-0 |
|---|---|
| SMILES | CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)NC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O |
Product Overview
Vinblastine-N-methyl amide sulfate (CAS 64448-88-0), with molecular formula C46H61N5O12S and molecular weight 907.40 g/mol. IUPAC: methyl 13-[11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-8-methyl-10-(methylcarbamoyl)-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraene-13-carboxylate;sulfuric acid.
Chemical Property Profile of Vinblastine-N-methyl amide sulfate
Property Insights of Vinblastine-N-methyl amide sulfate
The XLogP value of 2.9111 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Vinblastine-N-methyl amide sulfate. The TPSA of 231.5 Ų indicates high polarity, suggesting Vinblastine-N-methyl amide sulfate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Vinblastine-N-methyl amide sulfate has 6 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Vinblastine-N-methyl amide sulfate?
The CAS number of Vinblastine-N-methyl amide sulfate is 64448-88-0.
What is the molecular formula of Vinblastine-N-methyl amide sulfate?
The molecular formula of Vinblastine-N-methyl amide sulfate is C46H61N5O12S.
What is the molecular weight of Vinblastine-N-methyl amide sulfate?
The molecular weight of Vinblastine-N-methyl amide sulfate is 907.40 g/mol.
Where can I buy Vinblastine-N-methyl amide sulfate?
You can request a quote for Vinblastine-N-methyl amide sulfate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Vinblastine-N-methyl amide sulfate?
Yes, KEHONG BIO provides custom synthesis services for Vinblastine-N-methyl amide sulfate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.