2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile structure

2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile

TL;DR: 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile (CAS 64446-15-7) is a chemical compound with molecular formula C16H10ClN3O and molecular weight 295.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(Z)-2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyprop-2-enenitrile

Also Known As: BAS 00417096, 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile, (Z)-2-(1H-benzo[d]imidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile, (Z)-2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyprop-2-enenitrile, 2-(1H-Benzoimidazol-2-yl)-3-(4-chloro-phenyl)-3-hydroxy-acrylonitrile

CAS: 64446-15-7
Molecular Formula C16H10ClN3O
Molecular Weight 295.05 g/mol
LogP 4.16618
Topological Polar Surface Area 72.7 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 295.05124
Heavy Atoms 21
Complexity 839.4235

Chemical Identifiers

CAS Number 64446-15-7
SMILES C1=CC=C2C(=C1)NC(=N2)/C(=C(/C3=CC=C(C=C3)Cl)\O)/C#N

Product Overview

2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile (CAS 64446-15-7), with molecular formula C16H10ClN3O and molecular weight 295.05 g/mol. IUPAC: (Z)-2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyprop-2-enenitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile

XLogP
4.16618
TPSA (Topological Polar Surface Area)
72.7
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
21
Complexity
839.4235
Exact Mass
295.05124
Monoisotopic Mass
295.05124
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile

The XLogP value of 4.16618 indicates that 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile. Following Lipinski's Rule of Five, 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile?

The CAS number of 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile is 64446-15-7.

What is the molecular formula of 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile?

The molecular formula of 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile is C16H10ClN3O.

What is the molecular weight of 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile?

The molecular weight of 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile is 295.05 g/mol.

Where can I buy 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile?

You can request a quote for 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile?

Yes, KEHONG BIO provides custom synthesis services for 2-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-3-hydroxyacrylonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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