2-Hydroxychalcone
TL;DR: 2-Hydroxychalcone (CAS 644-87-1) is a chemical compound with molecular formula C15H12O2 and molecular weight 224.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one
Also Known As: 2-Hydroxychalcone, Salicylalacetophenone, o-Hydroxychalcone, Chalcone, 1, (E)-2-Hydroxychalcone
| Molecular Formula | C15H12O2 |
|---|---|
| Molecular Weight | 224.08 g/mol |
| LogP | 3.2883 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 224.08372 |
| Heavy Atoms | 17 |
| Complexity | 541.8581 |
Chemical Identifiers
| CAS Number | 644-87-1 |
|---|---|
| SMILES | C1=CC=C(C=C1)C(=O)/C=C/C2=CC=CC=C2O |
Product Overview
2-Hydroxychalcone (CAS 644-87-1), with molecular formula C15H12O2 and molecular weight 224.08 g/mol. IUPAC: (E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one.
Chemical Property Profile of 2-Hydroxychalcone
Property Insights of 2-Hydroxychalcone
The XLogP value of 3.2883 indicates that 2-Hydroxychalcone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, 2-Hydroxychalcone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Hydroxychalcone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Hydroxychalcone?
The CAS number of 2-Hydroxychalcone is 644-87-1.
What is the molecular formula of 2-Hydroxychalcone?
The molecular formula of 2-Hydroxychalcone is C15H12O2.
What is the molecular weight of 2-Hydroxychalcone?
The molecular weight of 2-Hydroxychalcone is 224.08 g/mol.
Where can I buy 2-Hydroxychalcone?
You can request a quote for 2-Hydroxychalcone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Hydroxychalcone?
Yes, KEHONG BIO provides custom synthesis services for 2-Hydroxychalcone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.