Hydroxychalcone
TL;DR: Hydroxychalcone (CAS 644-78-0) is a chemical compound with molecular formula C15H12O2 and molecular weight 224.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one
Also Known As: 2-Hydroxychalcone, hydroxychalcone, 3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one, 3-(2-hydroxy-phenyl)-1-phenyl-propenone, 3-(2-hydroxyphenyl)-1-phenyl-2-propen-1-one
| Molecular Formula | C15H12O2 |
|---|---|
| Molecular Weight | 224.08 g/mol |
| LogP | 3.3 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 224.08372 |
| Heavy Atoms | 17 |
| Complexity | 277.0 |
Chemical Identifiers
| CAS Number | 644-78-0 |
|---|---|
| SMILES | C1=CC=C(C=C1)C(=O)C=CC2=CC=CC=C2O |
| InChIKey | UDOOPSJCRMKSGL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 15 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Hydroxychalcone (CAS 644-78-0), with molecular formula C15H12O2 and molecular weight 224.08 g/mol. IUPAC: 3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one.
Chemical Property Profile of Hydroxychalcone
Property Insights of Hydroxychalcone
The XLogP value of 3.3 indicates that Hydroxychalcone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, Hydroxychalcone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Hydroxychalcone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Hydroxychalcone?
The CAS number of Hydroxychalcone is 644-78-0.
What is the molecular formula of Hydroxychalcone?
The molecular formula of Hydroxychalcone is C15H12O2.
What is the molecular weight of Hydroxychalcone?
The molecular weight of Hydroxychalcone is 224.08 g/mol.
Where can I buy Hydroxychalcone?
You can request a quote for Hydroxychalcone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Hydroxychalcone?
Yes, KEHONG BIO provides custom synthesis services for Hydroxychalcone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.