Khaplofoline
TL;DR: Khaplofoline (CAS 6431-83-0) is a chemical compound with molecular formula C14H15NO2 and molecular weight 229.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,2-dimethyl-4,10-dihydro-3H-pyrano[2,3-b]quinolin-5-one
Also Known As: Khaplofoline, Haplofoline, 2,2-Dimethyl-2,3,4,10-tetrahydro-5H-pyrano[2,3-b]quinolin-5-one, 2,2-dimethyl-4,10-dihydro-3H-pyrano[2,3-b]quinolin-5-one, AE-562/12222597
| Molecular Formula | C14H15NO2 |
|---|---|
| Molecular Weight | 229.11 g/mol |
| LogP | 2.8 |
| Topological Polar Surface Area | 38.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 229.11028 |
| Heavy Atoms | 17 |
| Complexity | 384.0 |
Chemical Identifiers
| CAS Number | 6431-83-0 |
|---|---|
| SMILES | CC1(CCC2=C(O1)NC3=CC=CC=C3C2=O)C |
| InChIKey | WRCTUFLKPSXQDM-UHFFFAOYSA-N |
Product Overview
Khaplofoline (CAS 6431-83-0), with molecular formula C14H15NO2 and molecular weight 229.11 g/mol. IUPAC: 2,2-dimethyl-4,10-dihydro-3H-pyrano[2,3-b]quinolin-5-one.
Chemical Property Profile of Khaplofoline
Property Insights of Khaplofoline
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Khaplofoline. With a topological polar surface area (TPSA) of 38.3 Ų, Khaplofoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Khaplofoline has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Khaplofoline?
The CAS number of Khaplofoline is 6431-83-0.
What is the molecular formula of Khaplofoline?
The molecular formula of Khaplofoline is C14H15NO2.
What is the molecular weight of Khaplofoline?
The molecular weight of Khaplofoline is 229.11 g/mol.
Where can I buy Khaplofoline?
You can request a quote for Khaplofoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Khaplofoline?
Yes, KEHONG BIO provides custom synthesis services for Khaplofoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.