Disnogamycin
TL;DR: Disnogamycin (CAS 64267-46-5) is a chemical compound with molecular formula C37H47NO14 and molecular weight 729.30 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R,10S,12R,21R,22S,23R,24R)-23-(dimethylamino)-4,8,12,22,24-pentahydroxy-1,12-dimethyl-10-[(2R,3R,4R,5S,6S)-3,4,5-trimethoxy-4,6-dimethyloxan-2-yl]oxy-20,25-dioxahexacyclo[19.3.1.02,19.05,18.07,16.09,14]pentacosa-2,4,7(16),8,14,18-hexaene-6,17-dione
Also Known As: Disnogamycin, Nogamycin, dis-Nogamycin, 2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-9,16-dione, 3,4,5,6,11,12,13,14-octahydro-11-((6-deoxy-3-C-methyl-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy)-4-(dimethylamino)-3,5,8,10,13-pentahydroxy-6,13-dimethyl-, (2-alpha,3-beta,4-alpha,5-beta,6-alpha,11-beta,13-alpha)-(+)-, (1R,10S,12R,21R,22S,23R,24R)-23-(dimethylamino)-4,8,12,22,24-pentahydroxy-1,12-dimethyl-10-{[(2R,3R,4R,5S,6S)-3,4,5-trimethoxy-4,6-dimethyloxan-2-yl]oxy}-20,25-dioxahexacyclo[19.3.1.02,19.05,18.07,16.09,14]pentacosa-2,4,7(16),8,14,18-hexaene-6,17-dione
| Molecular Formula | C37H47NO14 |
|---|---|
| Molecular Weight | 729.30 g/mol |
| LogP | 0.9 |
| Topological Polar Surface Area | 203.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 15 |
| Rotatable Bonds | 6 |
| Exact Mass | 729.2997 |
| Heavy Atoms | 52 |
| Complexity | 1390.0 |
Chemical Identifiers
| CAS Number | 64267-46-5 |
|---|---|
| SMILES | C[C@H]1[C@@H]([C@@]([C@H]([C@@H](O1)O[C@H]2C[C@](CC3=CC4=C(C(=C23)O)C(=O)C5=C(C=C6C(=C5C4=O)O[C@H]7[C@H]([C@@H]([C@H]([C@@]6(O7)C)O)N(C)C)O)O)(C)O)OC)(C)OC)OC |
| InChIKey | NNEGMXMRXKXKMQ-ZEOBNFASSA-N |
Product Overview
Disnogamycin (CAS 64267-46-5), with molecular formula C37H47NO14 and molecular weight 729.30 g/mol. IUPAC: (1R,10S,12R,21R,22S,23R,24R)-23-(dimethylamino)-4,8,12,22,24-pentahydroxy-1,12-dimethyl-10-[(2R,3R,4R,5S,6S)-3,4,5-trimethoxy-4,6-dimethyloxan-2-yl]oxy-20,25-dioxahexacyclo[19.3.1.02,19.05,18.07,16.09,14]pentacosa-2,4,7(16),8,14,18-hexaene-6,17-dione.
Chemical Property Profile of Disnogamycin
Property Insights of Disnogamycin
The XLogP value of 0.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Disnogamycin. The TPSA of 203.0 Ų indicates high polarity, suggesting Disnogamycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Disnogamycin has 5 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Disnogamycin?
The CAS number of Disnogamycin is 64267-46-5.
What is the molecular formula of Disnogamycin?
The molecular formula of Disnogamycin is C37H47NO14.
What is the molecular weight of Disnogamycin?
The molecular weight of Disnogamycin is 729.30 g/mol.
Where can I buy Disnogamycin?
You can request a quote for Disnogamycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Disnogamycin?
Yes, KEHONG BIO provides custom synthesis services for Disnogamycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.