Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride structure

Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride

TL;DR: Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride (CAS 64038-00-2) is a chemical compound with molecular formula C13H11ClF2N2O2 and molecular weight 300.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[3-(difluoromethoxy)phenyl]pyridine-3-carboxamide;hydrochloride

Also Known As: starbld0034724, Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride, N-(m-Difluoromethoxyphenyl)nicotinamide hydrochloride, m-Difluoromethoxyphenylamide of nicotinic acid hydrochloride, N-(3-(Difluoromethoxy)phenyl)nicotinamide hydrochloride

CAS: 64038-00-2
Molecular Formula C13H11ClF2N2O2
Molecular Weight 300.05 g/mol
LogP 3.36
Topological Polar Surface Area 51.2 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 4
Exact Mass 300.0477
Heavy Atoms 20
Complexity 302.0

Chemical Identifiers

CAS Number 64038-00-2
SMILES C1=CC(=CC(=C1)OC(F)F)NC(=O)C2=CN=CC=C2.Cl
InChIKey FNUKUPRWKAMWNL-UHFFFAOYSA-N

Product Overview

Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride (CAS 64038-00-2), with molecular formula C13H11ClF2N2O2 and molecular weight 300.05 g/mol. IUPAC: N-[3-(difluoromethoxy)phenyl]pyridine-3-carboxamide;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride

XLogP
3.36
TPSA (Topological Polar Surface Area)
51.2
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
20
Complexity
302.0
Exact Mass
300.0477
Monoisotopic Mass
300.0477
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride

The XLogP value of 3.36 indicates that Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.2 Ų, Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride?

The CAS number of Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride is 64038-00-2.

What is the molecular formula of Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride?

The molecular formula of Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride is C13H11ClF2N2O2.

What is the molecular weight of Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride?

The molecular weight of Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride is 300.05 g/mol.

Where can I buy Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride?

You can request a quote for Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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