2-Chloro-6-(1-piperazinyl)pyrazine
TL;DR: 2-Chloro-6-(1-piperazinyl)pyrazine (CAS 64022-27-1) is a chemical compound with molecular formula C8H11ClN4 and molecular weight 198.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-6-piperazin-1-ylpyrazine
Also Known As: 2-Chloro-6-(1-piperazinyl)pyrazine, 2-chloro-6-(piperazin-1-yl)pyrazine, 2-chloro-6-piperazin-1-ylpyrazine, 6-Chloro-2-(1-piperazinyl)pyrazine, MK 212
| Molecular Formula | C8H11ClN4 |
|---|---|
| Molecular Weight | 198.07 g/mol |
| LogP | 0.5 |
| Topological Polar Surface Area | 41.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 198.06723 |
| Heavy Atoms | 13 |
| Complexity | 160.0 |
Chemical Identifiers
| CAS Number | 64022-27-1 |
|---|---|
| SMILES | C1CN(CCN1)C2=CN=CC(=N2)Cl |
| InChIKey | CJAWPFJGFFNXQI-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2-Chloro-6-(1-piperazinyl)pyrazine (CAS 64022-27-1), with molecular formula C8H11ClN4 and molecular weight 198.07 g/mol. IUPAC: 2-chloro-6-piperazin-1-ylpyrazine.
Chemical Property Profile of 2-Chloro-6-(1-piperazinyl)pyrazine
Property Insights of 2-Chloro-6-(1-piperazinyl)pyrazine
The XLogP value of 0.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Chloro-6-(1-piperazinyl)pyrazine. With a topological polar surface area (TPSA) of 41.1 Ų, 2-Chloro-6-(1-piperazinyl)pyrazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-6-(1-piperazinyl)pyrazine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-6-(1-piperazinyl)pyrazine?
The CAS number of 2-Chloro-6-(1-piperazinyl)pyrazine is 64022-27-1.
What is the molecular formula of 2-Chloro-6-(1-piperazinyl)pyrazine?
The molecular formula of 2-Chloro-6-(1-piperazinyl)pyrazine is C8H11ClN4.
What is the molecular weight of 2-Chloro-6-(1-piperazinyl)pyrazine?
The molecular weight of 2-Chloro-6-(1-piperazinyl)pyrazine is 198.07 g/mol.
Where can I buy 2-Chloro-6-(1-piperazinyl)pyrazine?
You can request a quote for 2-Chloro-6-(1-piperazinyl)pyrazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-6-(1-piperazinyl)pyrazine?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-6-(1-piperazinyl)pyrazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.