![3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide structure](/static/products/6381/638136-58-0.webp)
3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide
TL;DR: 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide (CAS 638136-58-0) is a chemical compound with molecular formula C22H17F3N2O3S and molecular weight 446.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide
Also Known As: 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide, 2,4-Dioxo-5-(3-phenyl-2-propen-1-ylidene)-N-[2-(trifluoromethyl)phenyl]-3-thiazolidinepropanamide, 3-[2,4-dioxo-5-(3-phenylprop-2-en-1-ylidene)-1,3-thiazolidin-3-yl]-N-[2-(trifluoromethyl)phenyl]propanamide
| Molecular Formula | C22H17F3N2O3S |
|---|---|
| Molecular Weight | 446.09 g/mol |
| LogP | 5.3267 |
| Topological Polar Surface Area | 66.48 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 446.0912 |
| Heavy Atoms | 31 |
| Complexity | 1049.4667 |
Chemical Identifiers
| CAS Number | 638136-58-0 |
|---|---|
| SMILES | C1=CC=C(C=C1)C=CC=C2C(=O)N(C(=O)S2)CCC(=O)NC3=CC=CC=C3C(F)(F)F |
Product Overview
3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide (CAS 638136-58-0), with molecular formula C22H17F3N2O3S and molecular weight 446.09 g/mol. IUPAC: 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide.
Chemical Property Profile of 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide
Property Insights of 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide
The XLogP value of 5.3267 indicates that 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.48 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide. Following Lipinski's Rule of Five, 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide?
The CAS number of 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide is 638136-58-0.
What is the molecular formula of 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide?
The molecular formula of 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide is C22H17F3N2O3S.
What is the molecular weight of 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide?
The molecular weight of 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide is 446.09 g/mol.
Where can I buy 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide?
You can request a quote for 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide?
Yes, KEHONG BIO provides custom synthesis services for 3-(5-cinnamylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-N-[2-(trifluoromethyl)phenyl]propanamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.