Codeine methochloride structure

Codeine methochloride

TL;DR: Codeine methochloride (CAS 63732-63-8) is a chemical compound with molecular formula C19H24ClNO3 and molecular weight 349.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(4R,4aR,7S,7aR,12bS)-9-methoxy-3,3-dimethyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7-ol chloride

Also Known As: Codeine methochloride, Morphinan-6-alpha-ol, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-, methochloride, 6-Hydroxy-3-methoxy-17,17-dimethyl-7,8-didehydro-4,5-epoxymorphinan-17-ium chloride, 6alpha-Hydroxy-3-methoxy-17,17-dimethyl-5alpha-7,8-didehydro-4,5-epoxymorphinan-17-ium chloride, Morphinanium, 7,8-didehydro-4,5-epoxy-6-hydroxy-3-methoxy-17,17-dimethyl-, chloride, (5.alpha.,6.alpha.)-

CAS: 63732-63-8
Molecular Formula C19H24ClNO3
Molecular Weight 349.14 g/mol
LogP -1.3503
Topological Polar Surface Area 38.69 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 1
Exact Mass 349.14447
Heavy Atoms 24
Complexity 731.56726

Chemical Identifiers

CAS Number 63732-63-8
SMILES C[N+]1(CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](C=C4)O)C.[Cl-]

Product Overview

Codeine methochloride (CAS 63732-63-8), with molecular formula C19H24ClNO3 and molecular weight 349.14 g/mol. IUPAC: (4R,4aR,7S,7aR,12bS)-9-methoxy-3,3-dimethyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7-ol chloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Codeine methochloride

XLogP
-1.3503
TPSA (Topological Polar Surface Area)
38.69
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
1
Heavy Atoms
24
Complexity
731.56726
Exact Mass
349.14447
Monoisotopic Mass
349.14447
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Codeine methochloride

The XLogP value of -1.3503 indicates that Codeine methochloride is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 38.69 Ų, Codeine methochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Codeine methochloride has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Codeine methochloride?

The CAS number of Codeine methochloride is 63732-63-8.

What is the molecular formula of Codeine methochloride?

The molecular formula of Codeine methochloride is C19H24ClNO3.

What is the molecular weight of Codeine methochloride?

The molecular weight of Codeine methochloride is 349.14 g/mol.

Where can I buy Codeine methochloride?

You can request a quote for Codeine methochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Codeine methochloride?

Yes, KEHONG BIO provides custom synthesis services for Codeine methochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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