4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine structure

4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine

TL;DR: 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine (CAS 63731-99-7) is a chemical compound with molecular formula C15H24ClN5S and molecular weight 341.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-chloro-6-(4-methylpiperazin-1-yl)-5-methylsulfanyl-2-piperidin-1-ylpyrimidine

Also Known As: 4-chloro-6-5-methylthio-2-piperidinopyrimidine, 4-Chloro-6- -5-methylthio-2-piperidinopyrimidine, 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine, 4-chloro-6-(4-methylpiperazin-1-yl)-5-(methylsulfanyl)-2-(piperidin-1-yl)pyrimidine, 4-chloro-6-(4-methylpiperazin-1-yl)-5-methylsulfanyl-2-(1-piperidyl)pyrimidine

CAS: 63731-99-7
Molecular Formula C15H24ClN5S
Molecular Weight 341.14 g/mol
LogP 2.594
Topological Polar Surface Area 35.5 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 3
Exact Mass 341.1441
Heavy Atoms 22
Complexity 512.8994

Chemical Identifiers

CAS Number 63731-99-7
SMILES CN1CCN(CC1)C2=C(C(=NC(=N2)N3CCCCC3)Cl)SC

Product Overview

4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine (CAS 63731-99-7), with molecular formula C15H24ClN5S and molecular weight 341.14 g/mol. IUPAC: 4-chloro-6-(4-methylpiperazin-1-yl)-5-methylsulfanyl-2-piperidin-1-ylpyrimidine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine

XLogP
2.594
TPSA (Topological Polar Surface Area)
35.5
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
3
Heavy Atoms
22
Complexity
512.8994
Exact Mass
341.1441
Monoisotopic Mass
341.1441
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine

The XLogP value of 2.594 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine. With a topological polar surface area (TPSA) of 35.5 Ų, 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine?

The CAS number of 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine is 63731-99-7.

What is the molecular formula of 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine?

The molecular formula of 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine is C15H24ClN5S.

What is the molecular weight of 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine?

The molecular weight of 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine is 341.14 g/mol.

Where can I buy 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine?

You can request a quote for 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine?

Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-6-(4-methylpiperazino)-5-methylthio-2-piperidinopyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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