Amorpholone structure

Amorpholone

TL;DR: Amorpholone (CAS 6364-21-2) is a chemical compound with molecular formula C23H20O7 and molecular weight 408.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

21-hydroxy-16,17-dimethoxy-6-prop-1-en-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-1(13),3(11),4(8),9,14,16,18-heptaen-12-one

Also Known As: Amorpholone, Aporpholone, 6-hydroxy-dehydro-rotenon, (2R)-12-hydroxy-6a,12a-dehydrorotenone, 1,2-Dihydro-12-hydroxy-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(12H)-one

CAS: 6364-21-2
Molecular Formula C23H20O7
Molecular Weight 408.12 g/mol
LogP 3.4
Topological Polar Surface Area 83.5 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 3
Exact Mass 408.1209
Heavy Atoms 30
Complexity 761.0

Chemical Identifiers

CAS Number 6364-21-2
SMILES CC(=C)C1CC2=C(O1)C=CC3=C2OC4=C(C3=O)C5=CC(=C(C=C5OC4O)OC)OC
InChIKey FQWPFJMIQXANSW-UHFFFAOYSA-N

Product Overview

Amorpholone (CAS 6364-21-2), with molecular formula C23H20O7 and molecular weight 408.12 g/mol. IUPAC: 21-hydroxy-16,17-dimethoxy-6-prop-1-en-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-1(13),3(11),4(8),9,14,16,18-heptaen-12-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Amorpholone

XLogP
3.4
TPSA (Topological Polar Surface Area)
83.5
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
3
Heavy Atoms
30
Complexity
761.0
Exact Mass
408.1209
Monoisotopic Mass
408.1209
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Amorpholone

The XLogP value of 3.4 indicates that Amorpholone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Amorpholone. Following Lipinski's Rule of Five, Amorpholone has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Amorpholone?

The CAS number of Amorpholone is 6364-21-2.

What is the molecular formula of Amorpholone?

The molecular formula of Amorpholone is C23H20O7.

What is the molecular weight of Amorpholone?

The molecular weight of Amorpholone is 408.12 g/mol.

Where can I buy Amorpholone?

You can request a quote for Amorpholone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Amorpholone?

Yes, KEHONG BIO provides custom synthesis services for Amorpholone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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