Colchicine, N-benzoyl-N-deacetyl-10-thio-
TL;DR: Colchicine, N-benzoyl-N-deacetyl-10-thio- (CAS 63620-47-3) is a chemical compound with molecular formula C27H27NO5S and molecular weight 477.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(7S)-1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]benzamide
Also Known As: N-Benzoyldeacetylthiocolchicine, Colchicine, N-benzoyl-N-deacetyl-10-thio-, 4-14-00-00959 (Beilstein Handbook Reference), Benzamide, N-(5,6,7,9-tetrahydro-10-(methylthio)-9-oxo-1,2,3-trimethoxybenzo(a)heptalen-7-yl)-, (S)-, N-[(7S)-1,2,3-Trimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]benzenecarboximidic acid
| Molecular Formula | C27H27NO5S |
|---|---|
| Molecular Weight | 477.16 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 99.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 477.16098 |
| Heavy Atoms | 34 |
| Complexity | 859.0 |
Chemical Identifiers
| CAS Number | 63620-47-3 |
|---|---|
| SMILES | COC1=C(C(=C2C(=C1)CC[C@@H](C3=CC(=O)C(=CC=C32)SC)NC(=O)C4=CC=CC=C4)OC)OC |
| InChIKey | AHNUEGAJJOXHHL-FQEVSTJZSA-N |
Product Overview
Colchicine, N-benzoyl-N-deacetyl-10-thio- (CAS 63620-47-3), with molecular formula C27H27NO5S and molecular weight 477.16 g/mol. IUPAC: N-[(7S)-1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]benzamide.
Chemical Property Profile of Colchicine, N-benzoyl-N-deacetyl-10-thio-
Property Insights of Colchicine, N-benzoyl-N-deacetyl-10-thio-
The XLogP value of 3.4 indicates that Colchicine, N-benzoyl-N-deacetyl-10-thio- is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 99.2 Ų falls within the moderate polarity range, balancing permeability and solubility for Colchicine, N-benzoyl-N-deacetyl-10-thio-. Following Lipinski's Rule of Five, Colchicine, N-benzoyl-N-deacetyl-10-thio- has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colchicine, N-benzoyl-N-deacetyl-10-thio-?
The CAS number of Colchicine, N-benzoyl-N-deacetyl-10-thio- is 63620-47-3.
What is the molecular formula of Colchicine, N-benzoyl-N-deacetyl-10-thio-?
The molecular formula of Colchicine, N-benzoyl-N-deacetyl-10-thio- is C27H27NO5S.
What is the molecular weight of Colchicine, N-benzoyl-N-deacetyl-10-thio-?
The molecular weight of Colchicine, N-benzoyl-N-deacetyl-10-thio- is 477.16 g/mol.
Where can I buy Colchicine, N-benzoyl-N-deacetyl-10-thio-?
You can request a quote for Colchicine, N-benzoyl-N-deacetyl-10-thio- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colchicine, N-benzoyl-N-deacetyl-10-thio-?
Yes, KEHONG BIO provides custom synthesis services for Colchicine, N-benzoyl-N-deacetyl-10-thio- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.