Apremilast Impurity 11
TL;DR: Apremilast Impurity 11 (CAS 635705-72-5) is a chemical compound with molecular formula C20H22N2O6S and molecular weight 418.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]isoindole-1,3-dione
Also Known As: Apremilast Impurity 11, 4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione, Benzenemethanol,2-fluoro-4-hydroxy-a-methyl, 1H-Isoindole-1,3(2H)-dione, 4-amino-2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-, 1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-
| Molecular Formula | C20H22N2O6S |
|---|---|
| Molecular Weight | 418.12 g/mol |
| LogP | 2.058 |
| Topological Polar Surface Area | 116.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 418.11984 |
| Heavy Atoms | 29 |
| Complexity | 1080.3741 |
Chemical Identifiers
| CAS Number | 635705-72-5 |
|---|---|
| SMILES | CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)N)OC |
Product Overview
Apremilast Impurity 11 (CAS 635705-72-5), with molecular formula C20H22N2O6S and molecular weight 418.12 g/mol. IUPAC: 4-amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]isoindole-1,3-dione.
Chemical Property Profile of Apremilast Impurity 11
Property Insights of Apremilast Impurity 11
The XLogP value of 2.058 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Apremilast Impurity 11. The TPSA of 116.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Apremilast Impurity 11. Following Lipinski's Rule of Five, Apremilast Impurity 11 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Apremilast Impurity 11?
The CAS number of Apremilast Impurity 11 is 635705-72-5.
What is the molecular formula of Apremilast Impurity 11?
The molecular formula of Apremilast Impurity 11 is C20H22N2O6S.
What is the molecular weight of Apremilast Impurity 11?
The molecular weight of Apremilast Impurity 11 is 418.12 g/mol.
Where can I buy Apremilast Impurity 11?
You can request a quote for Apremilast Impurity 11 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Apremilast Impurity 11?
Yes, KEHONG BIO provides custom synthesis services for Apremilast Impurity 11 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.