盐酸帕唑帕尼
TL;DR: 盐酸帕唑帕尼 (CAS 635702-64-6) is a chemical compound with molecular formula C30H42O6 and molecular weight 498.30 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
盐酸帕唑帕尼
[1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] deca-3,5-dienoate
Also Known As: pazopanib HCl, 4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl deca-3,5-dienoate, 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide hydrochloride
| Molecular Formula | C30H42O6 |
|---|---|
| Molecular Weight | 498.30 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 104.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Exact Mass | 498.29813 |
| Heavy Atoms | 36 |
| Complexity | 1030.0 |
Chemical Identifiers
| CAS Number | 635702-64-6 |
|---|---|
| SMILES | CCCCC=CC=CCC(=O)OC12CC(C3(C(C1C2(C)C)C=C(CC4(C3C=C(C4=O)C)O)CO)O)C |
| InChIKey | AZEXNJIEBDRVJS-UHFFFAOYSA-N |
Product Overview
盐酸帕唑帕尼 (CAS 635702-64-6), with molecular formula C30H42O6 and molecular weight 498.30 g/mol. IUPAC: [1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] deca-3,5-dienoate.
Chemical Property Profile of 盐酸帕唑帕尼
Property Insights of 盐酸帕唑帕尼
The XLogP value of 3.8 indicates that 盐酸帕唑帕尼 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 盐酸帕唑帕尼. Following Lipinski's Rule of Five, 盐酸帕唑帕尼 has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 盐酸帕唑帕尼?
The CAS number of 盐酸帕唑帕尼 is 635702-64-6.
What is the molecular formula of 盐酸帕唑帕尼?
The molecular formula of 盐酸帕唑帕尼 is C30H42O6.
What is the molecular weight of 盐酸帕唑帕尼?
The molecular weight of 盐酸帕唑帕尼 is 498.30 g/mol.
Where can I buy 盐酸帕唑帕尼?
You can request a quote for 盐酸帕唑帕尼 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 盐酸帕唑帕尼?
Yes, KEHONG BIO provides custom synthesis services for 盐酸帕唑帕尼 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.