3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate structure

3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate

TL;DR: 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate (CAS 6345-23-9) is a chemical compound with molecular formula C18H25O5P and molecular weight 352.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) dihydrogen phosphate

Also Known As: Estradiol phosphate, Polyestradiol phosphate, 3-hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate, (3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) dihydrogen phosphate

CAS: 6345-23-9
Molecular Formula C18H25O5P
Molecular Weight 352.14 g/mol
LogP 2.9
Topological Polar Surface Area 87.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 5
Rotatable Bonds 2
Exact Mass 352.14395
Heavy Atoms 24
Complexity 534.0

Chemical Identifiers

CAS Number 6345-23-9
SMILES CC12CCC3C(C1CCC2OP(=O)(O)O)CCC4=C3C=CC(=C4)O
InChIKey BBWXLCKRYRQQPL-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (15 patents)

Product Overview

3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate (CAS 6345-23-9), with molecular formula C18H25O5P and molecular weight 352.14 g/mol. IUPAC: (3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) dihydrogen phosphate.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate

XLogP
2.9
TPSA (Topological Polar Surface Area)
87.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
5
Rotatable Bonds
2
Heavy Atoms
24
Complexity
534.0
Exact Mass
352.14395
Monoisotopic Mass
352.14395
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate

The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate. The TPSA of 87.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate. Following Lipinski's Rule of Five, 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate?

The CAS number of 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate is 6345-23-9.

What is the molecular formula of 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate?

The molecular formula of 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate is C18H25O5P.

What is the molecular weight of 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate?

The molecular weight of 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate is 352.14 g/mol.

Where can I buy 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate?

You can request a quote for 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate?

Yes, KEHONG BIO provides custom synthesis services for 3-Hydroxyestra-1,3,5(10)-trien-17-yl dihydrogen phosphate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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