4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol
TL;DR: 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol (CAS 6341-49-7) is a chemical compound with molecular formula C16H18N2O and molecular weight 254.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(8-amino-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenol
Also Known As: Nomifensine M1, 4'-Hydroxynomifensine, Nomifensine, 4'-hydroxy-, NOMIFENSINE METABOLITE H2, 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol
| Molecular Formula | C16H18N2O |
|---|---|
| Molecular Weight | 254.14 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 49.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 254.1419 |
| Heavy Atoms | 19 |
| Complexity | 301.0 |
Chemical Identifiers
| CAS Number | 6341-49-7 |
|---|---|
| SMILES | CN1CC(C2=C(C1)C(=CC=C2)N)C3=CC=C(C=C3)O |
| InChIKey | IDYRXWOMWZHWEO-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol (CAS 6341-49-7), with molecular formula C16H18N2O and molecular weight 254.14 g/mol. IUPAC: 4-(8-amino-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenol.
Chemical Property Profile of 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol
Property Insights of 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol. With a topological polar surface area (TPSA) of 49.5 Ų, 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol?
The CAS number of 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol is 6341-49-7.
What is the molecular formula of 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol?
The molecular formula of 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol is C16H18N2O.
What is the molecular weight of 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol?
The molecular weight of 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol is 254.14 g/mol.
Where can I buy 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol?
You can request a quote for 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol?
Yes, KEHONG BIO provides custom synthesis services for 4-(8-Amino-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl)phenol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.