Withanolide S structure

Withanolide S

TL;DR: Withanolide S (CAS 63139-16-2) is a chemical compound with molecular formula C28H40O8 and molecular weight 504.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[1-hydroxy-1-(5,6,14,17-tetrahydroxy-10,13-dimethyl-1-oxo-6,7,8,9,11,12,15,16-octahydro-4H-cyclopenta[a]phenanthren-17-yl)ethyl]-4,5-dimethyl-2,3-dihydropyran-6-one

Also Known As: Withanolide S, WITHAFERIN DERIV B665685K000, 2-[1-hydroxy-1-(5,6,14,17-tetrahydroxy-10,13-dimethyl-1-oxo-6,7,8,9,11,12,15,16-octahydro-4H-cyclopenta[a]phenanthren-17-yl)ethyl]-4,5-dimethyl-2,3-dihydropyran-6-one, 5,6,14,17,20-Pentahydroxy-22,26-epoxyergosta-2,24-diene-1,26-dione, 2-[1-Hydroxy-1-(5,6,14,17-tetrahydroxy-10,13-dimethyl-1-oxo-6,7,8,9,11,12,15,16-octahydro-4H-cyclopenta[A]phenanthren-17-yl)ethyl]-4 ,5-dimethyl-2,3-dihydropyran-6-one

CAS: 63139-16-2
Molecular Formula C28H40O8
Molecular Weight 504.27 g/mol
LogP 0.8
Topological Polar Surface Area 145.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 8
Rotatable Bonds 2
Exact Mass 504.2723
Heavy Atoms 36
Complexity 1080.0

Chemical Identifiers

CAS Number 63139-16-2
SMILES CC1=C(C(=O)OC(C1)C(C)(C2(CCC3(C2(CCC4C3CC(C5(C4(C(=O)C=CC5)C)O)O)C)O)O)O)C
InChIKey PQZVBIJEPVKNOZ-UHFFFAOYSA-N

Product Overview

Withanolide S (CAS 63139-16-2), with molecular formula C28H40O8 and molecular weight 504.27 g/mol. IUPAC: 2-[1-hydroxy-1-(5,6,14,17-tetrahydroxy-10,13-dimethyl-1-oxo-6,7,8,9,11,12,15,16-octahydro-4H-cyclopenta[a]phenanthren-17-yl)ethyl]-4,5-dimethyl-2,3-dihydropyran-6-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Withanolide S

XLogP
0.8
TPSA (Topological Polar Surface Area)
145.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
8
Rotatable Bonds
2
Heavy Atoms
36
Complexity
1080.0
Exact Mass
504.2723
Monoisotopic Mass
504.2723
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Withanolide S

The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Withanolide S. The TPSA of 145.0 Ų indicates high polarity, suggesting Withanolide S may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Withanolide S has 5 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Withanolide S?

The CAS number of Withanolide S is 63139-16-2.

What is the molecular formula of Withanolide S?

The molecular formula of Withanolide S is C28H40O8.

What is the molecular weight of Withanolide S?

The molecular weight of Withanolide S is 504.27 g/mol.

Where can I buy Withanolide S?

You can request a quote for Withanolide S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Withanolide S?

Yes, KEHONG BIO provides custom synthesis services for Withanolide S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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