Costatolide
TL;DR: Costatolide (CAS 63023-58-5) is a chemical compound with molecular formula C22H26O5 and molecular weight 370.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(16S,17R,18S)-18-hydroxy-10,10,16,17-tetramethyl-6-propyl-3,9,15-trioxatetracyclo[12.4.0.02,7.08,13]octadeca-1(14),2(7),5,8(13),11-pentaen-4-one
Also Known As: Costatolide, (-)-Calanolide B, Calanolide A, Calanolide F, Costatolide (Calophyllum)
| Molecular Formula | C22H26O5 |
|---|---|
| Molecular Weight | 370.18 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 65.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 370.178 |
| Heavy Atoms | 27 |
| Complexity | 666.0 |
Chemical Identifiers
| CAS Number | 63023-58-5 |
|---|---|
| SMILES | CCCC1=CC(=O)OC2=C1C3=C(C=CC(O3)(C)C)C4=C2[C@H]([C@H]([C@@H](O4)C)C)O |
| InChIKey | NIDRYBLTWYFCFV-PZROIBLQSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Costatolide (CAS 63023-58-5), with molecular formula C22H26O5 and molecular weight 370.18 g/mol. IUPAC: (16S,17R,18S)-18-hydroxy-10,10,16,17-tetramethyl-6-propyl-3,9,15-trioxatetracyclo[12.4.0.02,7.08,13]octadeca-1(14),2(7),5,8(13),11-pentaen-4-one.
Chemical Property Profile of Costatolide
Property Insights of Costatolide
The XLogP value of 3.8 indicates that Costatolide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Costatolide. Following Lipinski's Rule of Five, Costatolide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Costatolide?
The CAS number of Costatolide is 63023-58-5.
What is the molecular formula of Costatolide?
The molecular formula of Costatolide is C22H26O5.
What is the molecular weight of Costatolide?
The molecular weight of Costatolide is 370.18 g/mol.
Where can I buy Costatolide?
You can request a quote for Costatolide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Costatolide?
Yes, KEHONG BIO provides custom synthesis services for Costatolide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.