Tadalafil
TL;DR: Tadalafil (CAS 629652-72-8) is a chemical compound with molecular formula C22H19N3O4 and molecular weight 389.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
Also Known As: Tadalafil, cis-Tadalafil, Tadalafil-d3, Cialis, Tadanafil
| Molecular Formula | C22H19N3O4 |
|---|---|
| Molecular Weight | 389.14 g/mol |
| LogP | 2.2113 |
| Topological Polar Surface Area | 74.87 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 389.13754 |
| Heavy Atoms | 29 |
| Complexity | 1184.0142 |
Chemical Identifiers
| CAS Number | 629652-72-8 |
|---|---|
| SMILES | CN1CC(=O)N2C(C1=O)CC3=C(C2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36 |
Product Overview
Tadalafil (CAS 629652-72-8), with molecular formula C22H19N3O4 and molecular weight 389.14 g/mol. IUPAC: 2-(1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione.
Chemical Property Profile of Tadalafil
Property Insights of Tadalafil
The XLogP value of 2.2113 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tadalafil. The TPSA of 74.87 Ų falls within the moderate polarity range, balancing permeability and solubility for Tadalafil. Following Lipinski's Rule of Five, Tadalafil has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tadalafil?
The CAS number of Tadalafil is 629652-72-8.
What is the molecular formula of Tadalafil?
The molecular formula of Tadalafil is C22H19N3O4.
What is the molecular weight of Tadalafil?
The molecular weight of Tadalafil is 389.14 g/mol.
Where can I buy Tadalafil?
You can request a quote for Tadalafil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tadalafil?
Yes, KEHONG BIO provides custom synthesis services for Tadalafil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.