Nortadalafil
TL;DR: Nortadalafil (CAS 629652-62-6) is a chemical compound with molecular formula C21H17N3O4 and molecular weight 375.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,8R)-2-(1,3-benzodioxol-5-yl)-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
Also Known As: Nortadalafil, Demethyltadalafil, N-Desmethyl Tadalafil, Demethyl Tadalafil, (+)-Nortadalafil
| Molecular Formula | C21H17N3O4 |
|---|---|
| Molecular Weight | 375.12 g/mol |
| LogP | 1.8691 |
| Topological Polar Surface Area | 83.66 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 375.12192 |
| Heavy Atoms | 28 |
| Complexity | 1151.7583 |
Chemical Identifiers
| CAS Number | 629652-62-6 |
|---|---|
| SMILES | C1[C@@H]2C(=O)NCC(=O)N2[C@@H](C3=C1C4=CC=CC=C4N3)C5=CC6=C(C=C5)OCO6 |
Product Overview
Nortadalafil (CAS 629652-62-6), with molecular formula C21H17N3O4 and molecular weight 375.12 g/mol. IUPAC: (2R,8R)-2-(1,3-benzodioxol-5-yl)-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione.
Chemical Property Profile of Nortadalafil
Property Insights of Nortadalafil
The XLogP value of 1.8691 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nortadalafil. The TPSA of 83.66 Ų falls within the moderate polarity range, balancing permeability and solubility for Nortadalafil. Following Lipinski's Rule of Five, Nortadalafil has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Nortadalafil?
The CAS number of Nortadalafil is 629652-62-6.
What is the molecular formula of Nortadalafil?
The molecular formula of Nortadalafil is C21H17N3O4.
What is the molecular weight of Nortadalafil?
The molecular weight of Nortadalafil is 375.12 g/mol.
Where can I buy Nortadalafil?
You can request a quote for Nortadalafil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Nortadalafil?
Yes, KEHONG BIO provides custom synthesis services for Nortadalafil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.