pyroglutamylhistidyl-N-ethylamide
TL;DR: pyroglutamylhistidyl-N-ethylamide (CAS 6288-49-9) is a chemical compound with molecular formula C13H19N5O3 and molecular weight 293.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-2-(ethylamino)-3-(1H-imidazol-5-yl)propanoyl]-5-oxopyrrolidine-2-carboxamide
Also Known As: Pglu-his-EA, Pyroglutamylhistidyl-N-ethylamide, L-Histidinamide, 5-oxo-L-prolyl-N-ethyl-, (2S)-N-[(2S)-2-(ethylamino)-3-(1H-imidazol-5-yl)propanoyl]-5-oxopyrrolidine-2-carboxamide, A-ethyl-n-{[(2s)-5-oxopyrrolidin-2-yl]carbonyl}-l-histidinamide
| Molecular Formula | C13H19N5O3 |
|---|---|
| Molecular Weight | 293.15 g/mol |
| LogP | -1.1 |
| Topological Polar Surface Area | 116.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 293.1488 |
| Heavy Atoms | 21 |
| Complexity | 415.0 |
Chemical Identifiers
| CAS Number | 6288-49-9 |
|---|---|
| SMILES | CCN[C@@H](CC1=CN=CN1)C(=O)NC(=O)[C@@H]2CCC(=O)N2 |
| InChIKey | XCPVMFCMIHVDPF-UWVGGRQHSA-N |
Product Overview
pyroglutamylhistidyl-N-ethylamide (CAS 6288-49-9), with molecular formula C13H19N5O3 and molecular weight 293.15 g/mol. IUPAC: (2S)-N-[(2S)-2-(ethylamino)-3-(1H-imidazol-5-yl)propanoyl]-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of pyroglutamylhistidyl-N-ethylamide
Property Insights of pyroglutamylhistidyl-N-ethylamide
The XLogP value of -1.1 indicates that pyroglutamylhistidyl-N-ethylamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 116.0 Ų falls within the moderate polarity range, balancing permeability and solubility for pyroglutamylhistidyl-N-ethylamide. Following Lipinski's Rule of Five, pyroglutamylhistidyl-N-ethylamide has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of pyroglutamylhistidyl-N-ethylamide?
The CAS number of pyroglutamylhistidyl-N-ethylamide is 6288-49-9.
What is the molecular formula of pyroglutamylhistidyl-N-ethylamide?
The molecular formula of pyroglutamylhistidyl-N-ethylamide is C13H19N5O3.
What is the molecular weight of pyroglutamylhistidyl-N-ethylamide?
The molecular weight of pyroglutamylhistidyl-N-ethylamide is 293.15 g/mol.
Where can I buy pyroglutamylhistidyl-N-ethylamide?
You can request a quote for pyroglutamylhistidyl-N-ethylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for pyroglutamylhistidyl-N-ethylamide?
Yes, KEHONG BIO provides custom synthesis services for pyroglutamylhistidyl-N-ethylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.