N(sup 1)-(2-Aminopropyl)bleomycinamide structure

N(sup 1)-(2-Aminopropyl)bleomycinamide

TL;DR: N(sup 1)-(2-Aminopropyl)bleomycinamide (CAS 62841-16-1) is a chemical compound with molecular formula C53H80N18O21S2 and molecular weight 1368.52 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[5-[[1-[2-[4-[4-(2-aminopropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate

Also Known As: DAP-BLM, N(sup 1)-(2-Aminopropyl)bleomycinamide, Bleomycinamide, N1-(2-aminopropyl)-, Bleomycinamide, N(sup 1)-(2-aminopropyl)-, [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[5-[[1-[2-[4-[4-(2-aminopropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate

CAS: 62841-16-1
Molecular Formula C53H80N18O21S2
Molecular Weight 1368.52 g/mol
LogP -8.62438
Topological Polar Surface Area 653.09 Ų
Hydrogen Bond Donors 21
Hydrogen Bond Acceptors 32
Rotatable Bonds 33
Exact Mass 1368.5187
Heavy Atoms 94
Complexity 3239.4937

Chemical Identifiers

CAS Number 62841-16-1
SMILES CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCC(C)N)O

Product Overview

N(sup 1)-(2-Aminopropyl)bleomycinamide (CAS 62841-16-1), with molecular formula C53H80N18O21S2 and molecular weight 1368.52 g/mol. IUPAC: [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[5-[[1-[2-[4-[4-(2-aminopropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of N(sup 1)-(2-Aminopropyl)bleomycinamide

XLogP
-8.62438
TPSA (Topological Polar Surface Area)
653.09
Hydrogen Bond Donors
21
Hydrogen Bond Acceptors
32
Rotatable Bonds
33
Heavy Atoms
94
Complexity
3239.4937
Exact Mass
1368.5187
Monoisotopic Mass
1368.5187
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N(sup 1)-(2-Aminopropyl)bleomycinamide

The XLogP value of -8.62438 indicates that N(sup 1)-(2-Aminopropyl)bleomycinamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 653.09 Ų indicates high polarity, suggesting N(sup 1)-(2-Aminopropyl)bleomycinamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, N(sup 1)-(2-Aminopropyl)bleomycinamide has 21 hydrogen bond donor(s) and 32 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of N(sup 1)-(2-Aminopropyl)bleomycinamide?

The CAS number of N(sup 1)-(2-Aminopropyl)bleomycinamide is 62841-16-1.

What is the molecular formula of N(sup 1)-(2-Aminopropyl)bleomycinamide?

The molecular formula of N(sup 1)-(2-Aminopropyl)bleomycinamide is C53H80N18O21S2.

What is the molecular weight of N(sup 1)-(2-Aminopropyl)bleomycinamide?

The molecular weight of N(sup 1)-(2-Aminopropyl)bleomycinamide is 1368.52 g/mol.

Where can I buy N(sup 1)-(2-Aminopropyl)bleomycinamide?

You can request a quote for N(sup 1)-(2-Aminopropyl)bleomycinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for N(sup 1)-(2-Aminopropyl)bleomycinamide?

Yes, KEHONG BIO provides custom synthesis services for N(sup 1)-(2-Aminopropyl)bleomycinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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