Morpholinopropylamino bleomycin structure

Morpholinopropylamino bleomycin

TL;DR: Morpholinopropylamino bleomycin (CAS 62841-14-9) is a chemical compound with molecular formula C57H86N18O22S2 and molecular weight 1438.56 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[3-hydroxy-5-[[3-hydroxy-1-[2-[4-[4-(3-morpholin-4-ylpropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-1-oxobutan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate

Also Known As: Mop-blm, Morpholinopropylamino bleomycin, N(sup 1)-(3-Morpholinopropyl)bleomycinamide, Bleomycinamide, N(sup 1)-(3-morpholinopropyl)-, Bleomycinamide, N1-[3-(4-morpholinyl)propyl]-

CAS: 62841-14-9
Molecular Formula C57H86N18O22S2
Molecular Weight 1438.56 g/mol
LogP -8.24928
Topological Polar Surface Area 639.54 Ų
Hydrogen Bond Donors 20
Hydrogen Bond Acceptors 33
Rotatable Bonds 35
Exact Mass 1438.5605
Heavy Atoms 99
Complexity 3369.2566

Chemical Identifiers

CAS Number 62841-14-9
SMILES CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCN7CCOCC7)O

Product Overview

Morpholinopropylamino bleomycin (CAS 62841-14-9), with molecular formula C57H86N18O22S2 and molecular weight 1438.56 g/mol. IUPAC: [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[3-hydroxy-5-[[3-hydroxy-1-[2-[4-[4-(3-morpholin-4-ylpropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-1-oxobutan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Morpholinopropylamino bleomycin

XLogP
-8.24928
TPSA (Topological Polar Surface Area)
639.54
Hydrogen Bond Donors
20
Hydrogen Bond Acceptors
33
Rotatable Bonds
35
Heavy Atoms
99
Complexity
3369.2566
Exact Mass
1438.5605
Monoisotopic Mass
1438.5605
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Morpholinopropylamino bleomycin

The XLogP value of -8.24928 indicates that Morpholinopropylamino bleomycin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 639.54 Ų indicates high polarity, suggesting Morpholinopropylamino bleomycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Morpholinopropylamino bleomycin has 20 hydrogen bond donor(s) and 33 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Morpholinopropylamino bleomycin?

The CAS number of Morpholinopropylamino bleomycin is 62841-14-9.

What is the molecular formula of Morpholinopropylamino bleomycin?

The molecular formula of Morpholinopropylamino bleomycin is C57H86N18O22S2.

What is the molecular weight of Morpholinopropylamino bleomycin?

The molecular weight of Morpholinopropylamino bleomycin is 1438.56 g/mol.

Where can I buy Morpholinopropylamino bleomycin?

You can request a quote for Morpholinopropylamino bleomycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Morpholinopropylamino bleomycin?

Yes, KEHONG BIO provides custom synthesis services for Morpholinopropylamino bleomycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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