![(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione structure](/static/products/627/627827-86-5.png)
(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione
概要：(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione（CAS 627827-86-5）是一种化学化合物，分子式为C24H26N4O5S，分子量为482.16 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
2-(2,5-dimethoxyphenyl)-3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-1-(3-imidazol-1-ylpropyl)-2H-pyrrol-5-one
又称：(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione, 1-(3-(1H-imidazol-1-yl)propyl)-5-(2,5-dimethoxyphenyl)-4-(2,4-dimethylthiazole-5-carbonyl)-3-hydroxy-1H-pyrrol-2(5H)-one, 2-(2,5-dimethoxyphenyl)-3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-1-(3-imidazol-1-ylpropyl)-2H-pyrrol-5-one
| 分子式 | C24H26N4O5S |
|---|---|
| 分子量 | 482.16 g/mol |
| LogP | 3.64224 |
| 拓扑极性表面积 | 106.78 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 8 |
| 可旋转键数 | 9 |
| 精确质量 | 482.16238 |
| 重原子数 | 34 |
| 复杂度 | 1248.2968 |
化学标识符
| CAS 编号 | 627827-86-5 |
|---|---|
| SMILES | CC1=C(SC(=N1)C)C(=O)C2=C(C(=O)N(C2C3=C(C=CC(=C3)OC)OC)CCCN4C=CN=C4)O |
产品概述
(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione（CAS 627827-86-5），分子式为C24H26N4O5S，分子量为482.16 g/mol。IUPAC名：2-(2,5-dimethoxyphenyl)-3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-1-(3-imidazol-1-ylpropyl)-2H-pyrrol-5-one。
(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione化学性质概览
属性洞察：(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione
(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione的XLogP值为3.64224，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为106.78 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione有1个氢键供体和8个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione的CAS号是多少？
(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione的CAS号为627827-86-5。
(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione的分子式是什么？
(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione的分子式为C24H26N4O5S。
(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione的分子量是多少？
(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione的分子量为482.16 g/mol。
在哪里可以购买(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione？
您可以直接向科弘生物询价(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione的定制合成服务？
是的，科弘生物提供(4E)-5-(2,5-dimethoxyphenyl)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]pyrrolidine-2,3-dione及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。