![(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione structure](/static/products/627/627823-76-1.png)
(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione
概要：(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione（CAS 627823-76-1）是一种化学化合物，分子式为C21H18N4O3S，分子量为406.11 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-2-pyridin-3-yl-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one
又称：(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione, 3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-2-pyridin-3-yl-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one, 4-(2,4-dimethylthiazole-5-carbonyl)-3-hydroxy-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one
| 分子式 | C21H18N4O3S |
|---|---|
| 分子量 | 406.11 g/mol |
| LogP | 3.32844 |
| 拓扑极性表面积 | 96.28 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 7 |
| 可旋转键数 | 5 |
| 精确质量 | 406.10995 |
| 重原子数 | 29 |
| 复杂度 | 1109.4696 |
化学标识符
| CAS 编号 | 627823-76-1 |
|---|---|
| SMILES | CC1=C(SC(=N1)C)C(=O)C2=C(C(=O)N(C2C3=CN=CC=C3)CC4=CN=CC=C4)O |
产品概述
(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione（CAS 627823-76-1），分子式为C21H18N4O3S，分子量为406.11 g/mol。IUPAC名：3-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-4-hydroxy-2-pyridin-3-yl-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one。
(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione化学性质概览
属性洞察：(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione
(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione的XLogP值为3.32844，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为96.28 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione有1个氢键供体和7个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione的CAS号是多少？
(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione的CAS号为627823-76-1。
(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione的分子式是什么？
(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione的分子式为C21H18N4O3S。
(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione的分子量是多少？
(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione的分子量为406.11 g/mol。
在哪里可以购买(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione？
您可以直接向科弘生物询价(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione的定制合成服务？
是的，科弘生物提供(4E)-4-[(2,4-dimethyl-1,3-thiazol-5-yl)(hydroxy)methylidene]-5-(pyridin-3-yl)-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。