Thalipine structure

Thalipine

TL;DR: Thalipine (CAS 62724-08-7) is a chemical compound with molecular formula C39H44N2O8 and molecular weight 668.31 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(1S)-1-[[2-[[(6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-yl]oxy]-5-hydroxy-4-methoxyphenyl]methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol

Also Known As: Thalipine, 2-Ethylhexyl isocyanatocarbonate, 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-((5-hydroxy-4-methoxy-2-((5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo(de,g)quinolin-9-yl)oxy)phenyl)methyl)-6-methoxy-2-methyl-, (S-(R*,R*))-, (S-(R*,R*))-1,2,3,4-Tetrahydro-1-((5-hydroxy-4-methoxy-2-((5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo(de,g)quinolin-9-yl)oxy)phenyl)methyl)-6-methoxy-2-methyl-7-isoquinolinol, (1S)-1-[(5-Hydroxy-4-methoxy-2-{[(6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-yl]oxy}phenyl)methyl]-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol

CAS: 62724-08-7
Molecular Formula C39H44N2O8
Molecular Weight 668.31 g/mol
LogP 6.4569
Topological Polar Surface Area 102.32 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 10
Rotatable Bonds 9
Exact Mass 668.30975
Heavy Atoms 49
Complexity 1924.6692

Chemical Identifiers

CAS Number 62724-08-7
SMILES CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC(=C(C=C43)OC)OC5=CC(=C(C=C5C[C@H]6C7=CC(=C(C=C7CCN6C)OC)O)O)OC)OC)OC

Product Overview

Thalipine (CAS 62724-08-7), with molecular formula C39H44N2O8 and molecular weight 668.31 g/mol. IUPAC: (1S)-1-[[2-[[(6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-yl]oxy]-5-hydroxy-4-methoxyphenyl]methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Thalipine

XLogP
6.4569
TPSA (Topological Polar Surface Area)
102.32
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
10
Rotatable Bonds
9
Heavy Atoms
49
Complexity
1924.6692
Exact Mass
668.30975
Monoisotopic Mass
668.30975
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thalipine

The XLogP value of 6.4569 indicates that Thalipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 102.32 Ų falls within the moderate polarity range, balancing permeability and solubility for Thalipine. Following Lipinski's Rule of Five, Thalipine has 2 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thalipine?

The CAS number of Thalipine is 62724-08-7.

What is the molecular formula of Thalipine?

The molecular formula of Thalipine is C39H44N2O8.

What is the molecular weight of Thalipine?

The molecular weight of Thalipine is 668.31 g/mol.

Where can I buy Thalipine?

You can request a quote for Thalipine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thalipine?

Yes, KEHONG BIO provides custom synthesis services for Thalipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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