普罗加比
TL;DR: 普罗加比 (CAS 62666-20-0) is a chemical compound with molecular formula C17H16ClFN2O2 and molecular weight 334.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
普罗加比
4-[[(4-chlorophenyl)-(5-fluoro-2-hydroxyphenyl)methylidene]amino]butanamide
Also Known As: Progabide, Halogabide, Gabren, Gabrene, Progabida
| Molecular Formula | C17H16ClFN2O2 |
|---|---|
| Molecular Weight | 334.09 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 75.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 334.08844 |
| Heavy Atoms | 23 |
| Complexity | 425.0 |
| Melting Point | 133-135 °C |
| Solubility | 70.9 |
Chemical Identifiers
| CAS Number | 62666-20-0 |
|---|---|
| SMILES | C1=CC(=CC=C1C(=NCCCC(=O)N)C2=C(C=CC(=C2)F)O)Cl |
| InChIKey | IBALRBWGSVJPAP-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 12 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
普罗加比 (CAS 62666-20-0), with molecular formula C17H16ClFN2O2 and molecular weight 334.09 g/mol. IUPAC: 4-[[(4-chlorophenyl)-(5-fluoro-2-hydroxyphenyl)methylidene]amino]butanamide.
Chemical Property Profile of 普罗加比
Property Insights of 普罗加比
The XLogP value of 3.0 indicates that 普罗加比 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 普罗加比. Following Lipinski's Rule of Five, 普罗加比 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 普罗加比?
The CAS number of 普罗加比 is 62666-20-0.
What is the molecular formula of 普罗加比?
The molecular formula of 普罗加比 is C17H16ClFN2O2.
What is the molecular weight of 普罗加比?
The molecular weight of 普罗加比 is 334.09 g/mol.
Where can I buy 普罗加比?
You can request a quote for 普罗加比 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 普罗加比?
Yes, KEHONG BIO provides custom synthesis services for 普罗加比 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.