![(4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione structure](/static/products/623/623544-12-7.png)
(4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione
TL;DR: (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione (CAS 623544-12-7) is a chemical compound with molecular formula C26H19FN2O5 and molecular weight 458.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2-fluorophenyl)-4-hydroxy-3-(7-methoxy-1-benzofuran-2-carbonyl)-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one
Also Known As: (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione, 2-(2-fluorophenyl)-4-hydroxy-3-(7-methoxy-1-benzofuran-2-carbonyl)-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one, 5-(2-fluorophenyl)-3-hydroxy-4-(7-methoxybenzofuran-2-carbonyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one
| Molecular Formula | C26H19FN2O5 |
|---|---|
| Molecular Weight | 458.13 g/mol |
| LogP | 4.754 |
| Topological Polar Surface Area | 92.87 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 458.1278 |
| Heavy Atoms | 34 |
| Complexity | 1444.1205 |
Chemical Identifiers
| CAS Number | 623544-12-7 |
|---|---|
| SMILES | COC1=CC=CC2=C1OC(=C2)C(=O)C3=C(C(=O)N(C3C4=CC=CC=C4F)CC5=CN=CC=C5)O |
Product Overview
(4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione (CAS 623544-12-7), with molecular formula C26H19FN2O5 and molecular weight 458.13 g/mol. IUPAC: 2-(2-fluorophenyl)-4-hydroxy-3-(7-methoxy-1-benzofuran-2-carbonyl)-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one.
Chemical Property Profile of (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione
Property Insights of (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione
The XLogP value of 4.754 indicates that (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 92.87 Ų falls within the moderate polarity range, balancing permeability and solubility for (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione. Following Lipinski's Rule of Five, (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione?
The CAS number of (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione is 623544-12-7.
What is the molecular formula of (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione?
The molecular formula of (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione is C26H19FN2O5.
What is the molecular weight of (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione?
The molecular weight of (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione is 458.13 g/mol.
Where can I buy (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione?
You can request a quote for (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione?
Yes, KEHONG BIO provides custom synthesis services for (4E)-5-(2-fluorophenyl)-4-[hydroxy(7-methoxy-1-benzofuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.