JAK3 inhibitor VI
TL;DR: JAK3 inhibitor VI (CAS 623175-20-2) is a chemical compound with molecular formula C18H13N3O and molecular weight 287.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3Z)-5-pyridin-3-yl-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-2-one
Also Known As: JAK3 Inhibitor VI, JAK3-IN-14, HSCI1_000385, SDCCGSBI-0086686.P003, J1.265.028K
| Molecular Formula | C18H13N3O |
|---|---|
| Molecular Weight | 287.11 g/mol |
| LogP | 3.5694 |
| Topological Polar Surface Area | 57.78 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 287.10587 |
| Heavy Atoms | 22 |
| Complexity | 864.6126 |
Chemical Identifiers
| CAS Number | 623175-20-2 |
|---|---|
| SMILES | C1=CC(=CN=C1)C2=CC\3=C(C=C2)NC(=O)/C3=C\C4=CC=CN4 |
Product Overview
JAK3 inhibitor VI (CAS 623175-20-2), with molecular formula C18H13N3O and molecular weight 287.11 g/mol. IUPAC: (3Z)-5-pyridin-3-yl-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-2-one.
Chemical Property Profile of JAK3 inhibitor VI
Property Insights of JAK3 inhibitor VI
The XLogP value of 3.5694 indicates that JAK3 inhibitor VI is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.78 Ų, JAK3 inhibitor VI exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, JAK3 inhibitor VI has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of JAK3 inhibitor VI?
The CAS number of JAK3 inhibitor VI is 623175-20-2.
What is the molecular formula of JAK3 inhibitor VI?
The molecular formula of JAK3 inhibitor VI is C18H13N3O.
What is the molecular weight of JAK3 inhibitor VI?
The molecular weight of JAK3 inhibitor VI is 287.11 g/mol.
Where can I buy JAK3 inhibitor VI?
You can request a quote for JAK3 inhibitor VI directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for JAK3 inhibitor VI?
Yes, KEHONG BIO provides custom synthesis services for JAK3 inhibitor VI and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.