MEK inhibitor II structure

MEK inhibitor II

TL;DR: MEK inhibitor II (CAS 623163-52-0) is a chemical compound with molecular formula C14H8ClNO4 and molecular weight 289.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(3-chloro-1,4-dioxonaphthalen-2-yl)pyrrolidine-2,5-dione

Also Known As: MEK Inhibitor II, 1-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)pyrrolidine-2,5-dione, HSCI1_000187, SDCCGSBI-0086772.P003, 2-Chloro-3-(N-succinimidyl)-1,4-naphthoquinone

CAS: 623163-52-0
Molecular Formula C14H8ClNO4
Molecular Weight 289.01 g/mol
LogP 1.3
Topological Polar Surface Area 71.5 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 1
Exact Mass 289.0142
Heavy Atoms 20
Complexity 550.0

Chemical Identifiers

CAS Number 623163-52-0
SMILES C1CC(=O)N(C1=O)C2=C(C(=O)C3=CC=CC=C3C2=O)Cl
InChIKey GYQSWJNGTWVFOL-UHFFFAOYSA-N

Product Overview

MEK inhibitor II (CAS 623163-52-0), with molecular formula C14H8ClNO4 and molecular weight 289.01 g/mol. IUPAC: 1-(3-chloro-1,4-dioxonaphthalen-2-yl)pyrrolidine-2,5-dione.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of MEK inhibitor II

XLogP
1.3
TPSA (Topological Polar Surface Area)
71.5
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
1
Heavy Atoms
20
Complexity
550.0
Exact Mass
289.0142
Monoisotopic Mass
289.0142
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of MEK inhibitor II

The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for MEK inhibitor II. The TPSA of 71.5 Ų falls within the moderate polarity range, balancing permeability and solubility for MEK inhibitor II. Following Lipinski's Rule of Five, MEK inhibitor II has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of MEK inhibitor II?

The CAS number of MEK inhibitor II is 623163-52-0.

What is the molecular formula of MEK inhibitor II?

The molecular formula of MEK inhibitor II is C14H8ClNO4.

What is the molecular weight of MEK inhibitor II?

The molecular weight of MEK inhibitor II is 289.01 g/mol.

Where can I buy MEK inhibitor II?

You can request a quote for MEK inhibitor II directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for MEK inhibitor II?

Yes, KEHONG BIO provides custom synthesis services for MEK inhibitor II and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?