Tylophorinine
TL;DR: Tylophorinine (CAS 62181-70-8) is a chemical compound with molecular formula C23H25NO4 and molecular weight 379.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(13aS,14R)-3,6,7-trimethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizin-14-ol
Also Known As: Pergularinine, TYLOPHORININE, (-)-Tylophorinin, (-)-Pergularinine, (-)-Tylophorinine
| Molecular Formula | C23H25NO4 |
|---|---|
| Molecular Weight | 379.18 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 51.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 379.17834 |
| Heavy Atoms | 28 |
| Complexity | 559.0 |
Chemical Identifiers
| CAS Number | 62181-70-8 |
|---|---|
| SMILES | COC1=CC2=C(C=C1)C3=C(CN4CCC[C@H]4[C@@H]3O)C5=CC(=C(C=C52)OC)OC |
| InChIKey | LAWAARLALKUFQQ-CVDCTZTESA-N |
Product Overview
Tylophorinine (CAS 62181-70-8), with molecular formula C23H25NO4 and molecular weight 379.18 g/mol. IUPAC: (13aS,14R)-3,6,7-trimethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizin-14-ol.
Chemical Property Profile of Tylophorinine
Property Insights of Tylophorinine
The XLogP value of 3.6 indicates that Tylophorinine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.2 Ų, Tylophorinine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tylophorinine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tylophorinine?
The CAS number of Tylophorinine is 62181-70-8.
What is the molecular formula of Tylophorinine?
The molecular formula of Tylophorinine is C23H25NO4.
What is the molecular weight of Tylophorinine?
The molecular weight of Tylophorinine is 379.18 g/mol.
Where can I buy Tylophorinine?
You can request a quote for Tylophorinine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tylophorinine?
Yes, KEHONG BIO provides custom synthesis services for Tylophorinine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.