AF-399/42289928
TL;DR: AF-399/42289928 (CAS 620543-86-4) is a chemical compound with molecular formula C20H23F3N4O and molecular weight 392.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4-methylpiperazin-1-yl)-[4-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]phenyl]methanone
Also Known As: AF-399/42289928, (4-methylpiperazin-1-yl){4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}methanone, (4-methylpiperazin-1-yl)-[4-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]phenyl]methanone, 4-methylpiperazinyl 4-[3-(trifluoromethyl)(1H-4,5,6,7-tetrahydroindazolyl)]phe nyl ketone, (4-methylpiperazin-1-yl)(4-(3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)methanone
| Molecular Formula | C20H23F3N4O |
|---|---|
| Molecular Weight | 392.18 g/mol |
| LogP | 3.1575 |
| Topological Polar Surface Area | 41.37 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 392.1824 |
| Heavy Atoms | 28 |
| Complexity | 864.81134 |
Chemical Identifiers
| CAS Number | 620543-86-4 |
|---|---|
| SMILES | CN1CCN(CC1)C(=O)C2=CC=C(C=C2)N3C4=C(CCCC4)C(=N3)C(F)(F)F |
Product Overview
AF-399/42289928 (CAS 620543-86-4), with molecular formula C20H23F3N4O and molecular weight 392.18 g/mol. IUPAC: (4-methylpiperazin-1-yl)-[4-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]phenyl]methanone.
Chemical Property Profile of AF-399/42289928
Property Insights of AF-399/42289928
The XLogP value of 3.1575 indicates that AF-399/42289928 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.37 Ų, AF-399/42289928 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/42289928 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/42289928?
The CAS number of AF-399/42289928 is 620543-86-4.
What is the molecular formula of AF-399/42289928?
The molecular formula of AF-399/42289928 is C20H23F3N4O.
What is the molecular weight of AF-399/42289928?
The molecular weight of AF-399/42289928 is 392.18 g/mol.
Where can I buy AF-399/42289928?
You can request a quote for AF-399/42289928 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/42289928?
Yes, KEHONG BIO provides custom synthesis services for AF-399/42289928 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.