![(2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE structure](/static/products/620/620108-43-2.png)
(2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE
TL;DR: (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE (CAS 620108-43-2) is a chemical compound with molecular formula C29H26N4O3 and molecular weight 478.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-N-(4-methylphenyl)-3-[2-(5-methyl-2-propan-2-ylphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enamide
Also Known As: (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE, (2E)-2-cyano-N-(4-methylphenyl)-3-{2-[5-methyl-2-(propan-2-yl)phenoxy]-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}prop-2-enamide, (E)-2-cyano-3-(2-(2-isopropyl-5-methylphenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-N-(p-tolyl)acrylamide, (E)-2-cyano-N-(4-methylphenyl)-3-[2-(5-methyl-2-propan-2-ylphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enamide
| Molecular Formula | C29H26N4O3 |
|---|---|
| Molecular Weight | 478.20 g/mol |
| LogP | 5.77272 |
| Topological Polar Surface Area | 96.49 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 478.2005 |
| Heavy Atoms | 36 |
| Complexity | 1575.4326 |
Chemical Identifiers
| CAS Number | 620108-43-2 |
|---|---|
| SMILES | CC1=CC=C(C=C1)NC(=O)/C(=C/C2=C(N=C3C=CC=CN3C2=O)OC4=C(C=CC(=C4)C)C(C)C)/C#N |
Product Overview
(2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE (CAS 620108-43-2), with molecular formula C29H26N4O3 and molecular weight 478.20 g/mol. IUPAC: (E)-2-cyano-N-(4-methylphenyl)-3-[2-(5-methyl-2-propan-2-ylphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enamide.
Chemical Property Profile of (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE
Property Insights of (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE
The XLogP value of 5.77272 indicates that (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 96.49 Ų falls within the moderate polarity range, balancing permeability and solubility for (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE. Following Lipinski's Rule of Five, (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE?
The CAS number of (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE is 620108-43-2.
What is the molecular formula of (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE?
The molecular formula of (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE is C29H26N4O3.
What is the molecular weight of (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE?
The molecular weight of (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE is 478.20 g/mol.
Where can I buy (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE?
You can request a quote for (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE?
Yes, KEHONG BIO provides custom synthesis services for (2E)-2-CYANO-3-{2-[5-METHYL-2-(PROPAN-2-YL)PHENOXY]-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-3-YL}-N-(4-METHYLPHENYL)PROP-2-ENAMIDE and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.