1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one
TL;DR: 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one (CAS 6199-39-9) is a chemical compound with molecular formula C20H12ClN3O5S and molecular weight 441.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one
Also Known As: 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one, 1-(4-Chlorophenyl)-3-hydroxy-5-(4-nitrophenyl)-4-(1,3-thiazole-2-carbonyl)-1,5-dihydro-2H-pyrrol-2-one, 1-(4-chlorophenyl)-3-hydroxy-5-(4-nitrophenyl)-4-(1,3-thiazole-2-carbonyl)-5H-pyrrol-2-one
| Molecular Formula | C20H12ClN3O5S |
|---|---|
| Molecular Weight | 441.02 g/mol |
| LogP | 4.4876 |
| Topological Polar Surface Area | 113.64 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 441.01862 |
| Heavy Atoms | 30 |
| Complexity | 1174.1658 |
Chemical Identifiers
| CAS Number | 6199-39-9 |
|---|---|
| SMILES | C1=CC(=CC=C1C2C(=C(C(=O)N2C3=CC=C(C=C3)Cl)O)C(=O)C4=NC=CS4)[N+](=O)[O-] |
Product Overview
1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one (CAS 6199-39-9), with molecular formula C20H12ClN3O5S and molecular weight 441.02 g/mol. IUPAC: 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one.
Chemical Property Profile of 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one
Property Insights of 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one
The XLogP value of 4.4876 indicates that 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 113.64 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one. Following Lipinski's Rule of Five, 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one?
The CAS number of 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one is 6199-39-9.
What is the molecular formula of 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one?
The molecular formula of 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one is C20H12ClN3O5S.
What is the molecular weight of 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one?
The molecular weight of 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one is 441.02 g/mol.
Where can I buy 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one?
You can request a quote for 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one?
Yes, KEHONG BIO provides custom synthesis services for 1-(4-chlorophenyl)-4-hydroxy-2-(4-nitrophenyl)-3-(1,3-thiazole-2-carbonyl)-2H-pyrrol-5-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.