Bleomycin-pyp
TL;DR: Bleomycin-pyp (CAS 61949-96-0) is a chemical compound with molecular formula C60H87N19O21S2 and molecular weight 1473.58 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[3-hydroxy-5-[[3-hydroxy-1-oxo-1-[2-[4-[4-[3-(2-pyridin-2-ylethylamino)propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]butan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate
Also Known As: Bleomycin-pyp, n1-[3-[[2-(2-pyridyl)ethyl]amino]propyl]bleomycinamide, Bleomycinamide, N(sup 1)-(3-((2-(2-pyridyl)ethyl)amino)propyl)-, [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[3-hydroxy-5-[[3-hydroxy-1-oxo-1-[2-[4-[4-[3-(2-pyridin-2-ylethylamino)propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]butan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate
| Molecular Formula | C60H87N19O21S2 |
|---|---|
| Molecular Weight | 1473.58 g/mol |
| LogP | -7.7 |
| Topological Polar Surface Area | 708.0 Ų |
| Hydrogen Bond Donors | 21 |
| Hydrogen Bond Acceptors | 33 |
| Rotatable Bonds | 39 |
| Exact Mass | 1473.5765 |
| Heavy Atoms | 102 |
| Complexity | 2730.0 |
Chemical Identifiers
| CAS Number | 61949-96-0 |
|---|---|
| SMILES | CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCNCCC7=CC=CC=N7)O |
| InChIKey | UAGBVOMVWIAELJ-UHFFFAOYSA-N |
Product Overview
Bleomycin-pyp (CAS 61949-96-0), with molecular formula C60H87N19O21S2 and molecular weight 1473.58 g/mol. IUPAC: [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[3-hydroxy-5-[[3-hydroxy-1-oxo-1-[2-[4-[4-[3-(2-pyridin-2-ylethylamino)propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]butan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate.
Chemical Property Profile of Bleomycin-pyp
Property Insights of Bleomycin-pyp
The XLogP value of -7.7 indicates that Bleomycin-pyp is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 708.0 Ų indicates high polarity, suggesting Bleomycin-pyp may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Bleomycin-pyp has 21 hydrogen bond donor(s) and 33 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bleomycin-pyp?
The CAS number of Bleomycin-pyp is 61949-96-0.
What is the molecular formula of Bleomycin-pyp?
The molecular formula of Bleomycin-pyp is C60H87N19O21S2.
What is the molecular weight of Bleomycin-pyp?
The molecular weight of Bleomycin-pyp is 1473.58 g/mol.
Where can I buy Bleomycin-pyp?
You can request a quote for Bleomycin-pyp directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bleomycin-pyp?
Yes, KEHONG BIO provides custom synthesis services for Bleomycin-pyp and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.