VU0605435-1
TL;DR: VU0605435-1 (CAS 618878-53-8) is a chemical compound with molecular formula C22H19ClN4O3 and molecular weight 422.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-4-[(4-chlorophenyl)-hydroxymethylidene]-1-(3-imidazol-1-ylpropyl)-5-pyridin-2-ylpyrrolidine-2,3-dione
Also Known As: VU0605435-1, AB00683480-01, 1-(3-(1H-imidazol-1-yl)propyl)-4-(4-chlorobenzoyl)-3-hydroxy-5-(pyridin-2-yl)-1H-pyrrol-2(5H)-one, F3226-0582, 4-(4-chlorobenzoyl)-3-hydroxy-1-[3-(1H-imidazol-1-yl)propyl]-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one
| Molecular Formula | C22H19ClN4O3 |
|---|---|
| Molecular Weight | 422.11 g/mol |
| LogP | 3.4435 |
| Topological Polar Surface Area | 88.32 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 422.11456 |
| Heavy Atoms | 30 |
| Complexity | 1079.3401 |
Chemical Identifiers
| CAS Number | 618878-53-8 |
|---|---|
| SMILES | C1=CC=NC(=C1)C2/C(=C(/C3=CC=C(C=C3)Cl)\O)/C(=O)C(=O)N2CCCN4C=CN=C4 |
Product Overview
VU0605435-1 (CAS 618878-53-8), with molecular formula C22H19ClN4O3 and molecular weight 422.11 g/mol. IUPAC: (4E)-4-[(4-chlorophenyl)-hydroxymethylidene]-1-(3-imidazol-1-ylpropyl)-5-pyridin-2-ylpyrrolidine-2,3-dione.
Chemical Property Profile of VU0605435-1
Property Insights of VU0605435-1
The XLogP value of 3.4435 indicates that VU0605435-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.32 Ų falls within the moderate polarity range, balancing permeability and solubility for VU0605435-1. Following Lipinski's Rule of Five, VU0605435-1 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of VU0605435-1?
The CAS number of VU0605435-1 is 618878-53-8.
What is the molecular formula of VU0605435-1?
The molecular formula of VU0605435-1 is C22H19ClN4O3.
What is the molecular weight of VU0605435-1?
The molecular weight of VU0605435-1 is 422.11 g/mol.
Where can I buy VU0605435-1?
You can request a quote for VU0605435-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for VU0605435-1?
Yes, KEHONG BIO provides custom synthesis services for VU0605435-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.