![(4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione structure](/static/products/618/618877-84-2.png)
(4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione
TL;DR: (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione (CAS 618877-84-2) is a chemical compound with molecular formula C18H19N3O3S and molecular weight 357.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-(dimethylamino)ethyl]-4-hydroxy-2-pyridin-2-yl-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one
Also Known As: (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione, 1-(2-(dimethylamino)ethyl)-3-hydroxy-5-(pyridin-2-yl)-4-(thiophene-2-carbonyl)-1H-pyrrol-2(5H)-one, 1-(2-dimethylaminoethyl)-3-hydroxy-5-pyridin-2-yl-4-(thiophene-2-carbonyl)-5H-pyrrol-2-one, 1-(2-dimethylaminoethyl)-4-hydroxy-2-pyridin-2-yl-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one
| Molecular Formula | C18H19N3O3S |
|---|---|
| Molecular Weight | 357.11 g/mol |
| LogP | 2.283 |
| Topological Polar Surface Area | 73.74 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 357.11472 |
| Heavy Atoms | 25 |
| Complexity | 800.23846 |
Chemical Identifiers
| CAS Number | 618877-84-2 |
|---|---|
| SMILES | CN(C)CCN1C(C(=C(C1=O)O)C(=O)C2=CC=CS2)C3=CC=CC=N3 |
Product Overview
(4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione (CAS 618877-84-2), with molecular formula C18H19N3O3S and molecular weight 357.11 g/mol. IUPAC: 1-[2-(dimethylamino)ethyl]-4-hydroxy-2-pyridin-2-yl-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one.
Chemical Property Profile of (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione
Property Insights of (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione
The XLogP value of 2.283 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione. The TPSA of 73.74 Ų falls within the moderate polarity range, balancing permeability and solubility for (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione. Following Lipinski's Rule of Five, (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione?
The CAS number of (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione is 618877-84-2.
What is the molecular formula of (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione?
The molecular formula of (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione is C18H19N3O3S.
What is the molecular weight of (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione?
The molecular weight of (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione is 357.11 g/mol.
Where can I buy (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione?
You can request a quote for (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione?
Yes, KEHONG BIO provides custom synthesis services for (4E)-1-[2-(dimethylamino)ethyl]-4-[hydroxy(thiophen-2-yl)methylidene]-5-(pyridin-2-yl)pyrrolidine-2,3-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.