![(4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione structure](/static/products/618/618863-95-9.png)
(4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
TL;DR: (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione (CAS 618863-95-9) is a chemical compound with molecular formula C25H20N2O4S and molecular weight 444.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(1-benzofuran-2-carbonyl)-4-hydroxy-2-(4-propan-2-ylphenyl)-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one
Also Known As: (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione, 3-(1-benzofuran-2-carbonyl)-4-hydroxy-2-(4-propan-2-ylphenyl)-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one, 4-(benzofuran-2-carbonyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one, 4-(benzofuran-2-carbonyl)-3-hydroxy-5-(4-propan-2-ylphenyl)-1-(1,3-thiazol-2-yl)-5H-pyrrol-2-one
| Molecular Formula | C25H20N2O4S |
|---|---|
| Molecular Weight | 444.11 g/mol |
| LogP | 5.7956 |
| Topological Polar Surface Area | 83.64 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 444.11438 |
| Heavy Atoms | 32 |
| Complexity | 1317.3782 |
Chemical Identifiers
| CAS Number | 618863-95-9 |
|---|---|
| SMILES | CC(C)C1=CC=C(C=C1)C2C(=C(C(=O)N2C3=NC=CS3)O)C(=O)C4=CC5=CC=CC=C5O4 |
Product Overview
(4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione (CAS 618863-95-9), with molecular formula C25H20N2O4S and molecular weight 444.11 g/mol. IUPAC: 3-(1-benzofuran-2-carbonyl)-4-hydroxy-2-(4-propan-2-ylphenyl)-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one.
Chemical Property Profile of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
Property Insights of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
The XLogP value of 5.7956 indicates that (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.64 Ų falls within the moderate polarity range, balancing permeability and solubility for (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione. Following Lipinski's Rule of Five, (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione?
The CAS number of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione is 618863-95-9.
What is the molecular formula of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione?
The molecular formula of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione is C25H20N2O4S.
What is the molecular weight of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione?
The molecular weight of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione is 444.11 g/mol.
Where can I buy (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione?
You can request a quote for (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione?
Yes, KEHONG BIO provides custom synthesis services for (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.