AF-399/41980910 structure

AF-399/41980910

TL;DR: AF-399/41980910 (CAS 618405-06-4) is a chemical compound with molecular formula C26H27N5O2S and molecular weight 473.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[4,5-dimethyl-3-[pyridin-3-yl-(4-pyridin-2-ylpiperazin-1-yl)methyl]thiophen-2-yl]furan-2-carboxamide

Also Known As: AF-399/41980910, F1396-0122, N-(4,5-dimethyl-3-((4-(pyridin-2-yl)piperazin-1-yl)(pyridin-3-yl)methyl)thiophen-2-yl)furan-2-carboxamide, N-(4,5-dimethyl-3-{[4-(pyridin-2-yl)piperazin-1-yl](pyridin-3-yl)methyl}thiophen-2-yl)furan-2-carboxamide, N-[4,5-dimethyl-3-[pyridin-3-yl-(4-pyridin-2-ylpiperazin-1-yl)methyl]thiophen-2-yl]furan-2-carboxamide

CAS: 618405-06-4
Molecular Formula C26H27N5O2S
Molecular Weight 473.19 g/mol
LogP 4.91184
Topological Polar Surface Area 74.5 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 6
Exact Mass 473.18854
Heavy Atoms 34
Complexity 1233.2087

Chemical Identifiers

CAS Number 618405-06-4
SMILES CC1=C(SC(=C1C(C2=CN=CC=C2)N3CCN(CC3)C4=CC=CC=N4)NC(=O)C5=CC=CO5)C

Product Overview

AF-399/41980910 (CAS 618405-06-4), with molecular formula C26H27N5O2S and molecular weight 473.19 g/mol. IUPAC: N-[4,5-dimethyl-3-[pyridin-3-yl-(4-pyridin-2-ylpiperazin-1-yl)methyl]thiophen-2-yl]furan-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AF-399/41980910

XLogP
4.91184
TPSA (Topological Polar Surface Area)
74.5
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
6
Heavy Atoms
34
Complexity
1233.2087
Exact Mass
473.18854
Monoisotopic Mass
473.18854
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AF-399/41980910

The XLogP value of 4.91184 indicates that AF-399/41980910 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 74.5 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/41980910. Following Lipinski's Rule of Five, AF-399/41980910 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AF-399/41980910?

The CAS number of AF-399/41980910 is 618405-06-4.

What is the molecular formula of AF-399/41980910?

The molecular formula of AF-399/41980910 is C26H27N5O2S.

What is the molecular weight of AF-399/41980910?

The molecular weight of AF-399/41980910 is 473.19 g/mol.

Where can I buy AF-399/41980910?

You can request a quote for AF-399/41980910 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AF-399/41980910?

Yes, KEHONG BIO provides custom synthesis services for AF-399/41980910 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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