2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione
TL;DR: 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione (CAS 618396-47-7) is a chemical compound with molecular formula C17H19BrN2OS and molecular weight 378.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4-thione
Also Known As: AS-871/41981383, 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione, F1404-0002, 2-(4-bromophenyl)-1-(3-hydroxypropyl)-1,4,5,6,7,8-hexahydroquinazoline-4-thione, 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4-thione
| Molecular Formula | C17H19BrN2OS |
|---|---|
| Molecular Weight | 378.04 g/mol |
| LogP | 4.30329 |
| Topological Polar Surface Area | 38.05 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 378.04016 |
| Heavy Atoms | 22 |
| Complexity | 724.6742 |
Chemical Identifiers
| CAS Number | 618396-47-7 |
|---|---|
| SMILES | C1CCC2=C(C1)C(=S)N=C(N2CCCO)C3=CC=C(C=C3)Br |
Product Overview
2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione (CAS 618396-47-7), with molecular formula C17H19BrN2OS and molecular weight 378.04 g/mol. IUPAC: 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4-thione.
Chemical Property Profile of 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione
Property Insights of 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione
The XLogP value of 4.30329 indicates that 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.05 Ų, 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione?
The CAS number of 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione is 618396-47-7.
What is the molecular formula of 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione?
The molecular formula of 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione is C17H19BrN2OS.
What is the molecular weight of 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione?
The molecular weight of 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione is 378.04 g/mol.
Where can I buy 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione?
You can request a quote for 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-bromophenyl)-1-(3-hydroxypropyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.