![1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine structure](/static/products/6183/618396-21-7.webp)
1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine
TL;DR: 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine (CAS 618396-21-7) is a chemical compound with molecular formula C18H20F2N2O3S and molecular weight 382.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(3,4-difluorophenyl)sulfonyl-4-(2-ethoxyphenyl)piperazine
Also Known As: 1-[(3,4-difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine, 1-(3,4-difluorobenzenesulfonyl)-4-(2-ethoxyphenyl)piperazine, 1-(3,4-difluorophenyl)sulfonyl-4-(2-ethoxyphenyl)piperazine, 4-{[4-(2-ethoxyphenyl)piperazinyl]sulfonyl}-1,2-difluorobenzene
| Molecular Formula | C18H20F2N2O3S |
|---|---|
| Molecular Weight | 382.12 g/mol |
| LogP | 2.8744 |
| Topological Polar Surface Area | 49.85 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 382.11627 |
| Heavy Atoms | 26 |
| Complexity | 881.755 |
Chemical Identifiers
| CAS Number | 618396-21-7 |
|---|---|
| SMILES | CCOC1=CC=CC=C1N2CCN(CC2)S(=O)(=O)C3=CC(=C(C=C3)F)F |
Product Overview
1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine (CAS 618396-21-7), with molecular formula C18H20F2N2O3S and molecular weight 382.12 g/mol. IUPAC: 1-(3,4-difluorophenyl)sulfonyl-4-(2-ethoxyphenyl)piperazine.
Chemical Property Profile of 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine
Property Insights of 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine
The XLogP value of 2.8744 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine. With a topological polar surface area (TPSA) of 49.85 Ų, 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine?
The CAS number of 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine is 618396-21-7.
What is the molecular formula of 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine?
The molecular formula of 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine is C18H20F2N2O3S.
What is the molecular weight of 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine?
The molecular weight of 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine is 382.12 g/mol.
Where can I buy 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine?
You can request a quote for 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-[(3,4-Difluorophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.