1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid
TL;DR: 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid (CAS 618382-85-7) is a chemical compound with molecular formula C15H12N2O2S and molecular weight 284.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(2-methylphenyl)-3-thiophen-2-ylpyrazole-5-carboxylic acid
Also Known As: 3-(Thiophen-2-yl)-1-(o-tolyl)-1H-pyrazole-5-carboxylic acid, 5243AH, 3-(Thiophen-2-yl)-1-o-tolyl-1H-pyrazole-5-carboxylic acid, 2-(2-methylphenyl)-5-thiophen-2-ylpyrazole-3-carboxylic acid, 5-thiophen-2-yl-2-o-tolyl-2h-pyrazole-3-carboxylic acid
| Molecular Formula | C15H12N2O2S |
|---|---|
| Molecular Weight | 284.06 g/mol |
| LogP | 3.60742 |
| Topological Polar Surface Area | 55.12 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 284.06195 |
| Heavy Atoms | 20 |
| Complexity | 760.0388 |
Chemical Identifiers
| CAS Number | 618382-85-7 |
|---|---|
| SMILES | CC1=CC=CC=C1N2C(=CC(=N2)C3=CC=CS3)C(=O)O |
Product Overview
1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid (CAS 618382-85-7), with molecular formula C15H12N2O2S and molecular weight 284.06 g/mol. IUPAC: 1-(2-methylphenyl)-3-thiophen-2-ylpyrazole-5-carboxylic acid.
Chemical Property Profile of 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid
Property Insights of 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid
The XLogP value of 3.60742 indicates that 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.12 Ų, 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid?
The CAS number of 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid is 618382-85-7.
What is the molecular formula of 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid?
The molecular formula of 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid is C15H12N2O2S.
What is the molecular weight of 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid?
The molecular weight of 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid is 284.06 g/mol.
Where can I buy 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid?
You can request a quote for 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for 1-(2-Methylphenyl)-3-(2-thienyl)-1H-pyrazole-5-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.