4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one
TL;DR: 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 618369-75-8) is a chemical compound with molecular formula C22H13ClN2O4S and molecular weight 436.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(1-benzofuran-2-carbonyl)-2-(4-chlorophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one
Also Known As: 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one, F3226-1380, 4-(1-benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(1,3-thiazol-2-yl)-2,5-dihydro-1H-pyrrol-2-one, 3-(1-benzofuran-2-carbonyl)-2-(4-chlorophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one, (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-5-(4-chlorophenyl)-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
| Molecular Formula | C22H13ClN2O4S |
|---|---|
| Molecular Weight | 436.03 g/mol |
| LogP | 5.3256 |
| Topological Polar Surface Area | 83.64 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 436.02844 |
| Heavy Atoms | 30 |
| Complexity | 1275.6842 |
Chemical Identifiers
| CAS Number | 618369-75-8 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C=C(O2)C(=O)C3=C(C(=O)N(C3C4=CC=C(C=C4)Cl)C5=NC=CS5)O |
Product Overview
4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 618369-75-8), with molecular formula C22H13ClN2O4S and molecular weight 436.03 g/mol. IUPAC: 3-(1-benzofuran-2-carbonyl)-2-(4-chlorophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one.
Chemical Property Profile of 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one
Property Insights of 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one
The XLogP value of 5.3256 indicates that 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.64 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one. Following Lipinski's Rule of Five, 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one?
The CAS number of 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one is 618369-75-8.
What is the molecular formula of 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one?
The molecular formula of 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one is C22H13ClN2O4S.
What is the molecular weight of 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one?
The molecular weight of 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one is 436.03 g/mol.
Where can I buy 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one?
You can request a quote for 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.