VU0605427-1
TL;DR: VU0605427-1 (CAS 618369-37-2) is a chemical compound with molecular formula C25H20FN3O4 and molecular weight 445.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(1-benzofuran-2-carbonyl)-2-(4-fluorophenyl)-4-hydroxy-1-(3-imidazol-1-ylpropyl)-2H-pyrrol-5-one
Also Known As: VU0605427-1, 1-(3-(1H-imidazol-1-yl)propyl)-4-(benzofuran-2-carbonyl)-5-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one, AB00683478-01, F3226-0540, 4-(1-benzofuran-2-carbonyl)-5-(4-fluorophenyl)-3-hydroxy-1-[3-(1H-imidazol-1-yl)propyl]-2,5-dihydro-1H-pyrrol-2-one
| Molecular Formula | C25H20FN3O4 |
|---|---|
| Molecular Weight | 445.14 g/mol |
| LogP | 4.437 |
| Topological Polar Surface Area | 88.57 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 445.1438 |
| Heavy Atoms | 33 |
| Complexity | 1323.0884 |
Chemical Identifiers
| CAS Number | 618369-37-2 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C=C(O2)C(=O)C3=C(C(=O)N(C3C4=CC=C(C=C4)F)CCCN5C=CN=C5)O |
Product Overview
VU0605427-1 (CAS 618369-37-2), with molecular formula C25H20FN3O4 and molecular weight 445.14 g/mol. IUPAC: 3-(1-benzofuran-2-carbonyl)-2-(4-fluorophenyl)-4-hydroxy-1-(3-imidazol-1-ylpropyl)-2H-pyrrol-5-one.
Chemical Property Profile of VU0605427-1
Property Insights of VU0605427-1
The XLogP value of 4.437 indicates that VU0605427-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.57 Ų falls within the moderate polarity range, balancing permeability and solubility for VU0605427-1. Following Lipinski's Rule of Five, VU0605427-1 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of VU0605427-1?
The CAS number of VU0605427-1 is 618369-37-2.
What is the molecular formula of VU0605427-1?
The molecular formula of VU0605427-1 is C25H20FN3O4.
What is the molecular weight of VU0605427-1?
The molecular weight of VU0605427-1 is 445.14 g/mol.
Where can I buy VU0605427-1?
You can request a quote for VU0605427-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for VU0605427-1?
Yes, KEHONG BIO provides custom synthesis services for VU0605427-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.