![(4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione structure](/static/products/618/618363-74-9.png)
(4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione
TL;DR: (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione (CAS 618363-74-9) is a chemical compound with molecular formula C22H22N2O4S and molecular weight 410.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(1-benzofuran-2-carbonyl)-1-[3-(dimethylamino)propyl]-4-hydroxy-2-thiophen-2-yl-2H-pyrrol-5-one
Also Known As: (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione, 3-(1-benzofuran-2-carbonyl)-1-[3-(dimethylamino)propyl]-4-hydroxy-2-thiophen-2-yl-2H-pyrrol-5-one, 4-(benzofuran-2-carbonyl)-1-(3-(dimethylamino)propyl)-3-hydroxy-5-(thiophen-2-yl)-1H-pyrrol-2(5H)-one, 4-(benzofuran-2-carbonyl)-1-(3-dimethylaminopropyl)-3-hydroxy-5-thiophen-2-yl-5H-pyrrol-2-one
| Molecular Formula | C22H22N2O4S |
|---|---|
| Molecular Weight | 410.13 g/mol |
| LogP | 4.0243 |
| Topological Polar Surface Area | 73.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 410.13004 |
| Heavy Atoms | 29 |
| Complexity | 1048.3856 |
Chemical Identifiers
| CAS Number | 618363-74-9 |
|---|---|
| SMILES | CN(C)CCCN1C(C(=C(C1=O)O)C(=O)C2=CC3=CC=CC=C3O2)C4=CC=CS4 |
Product Overview
(4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione (CAS 618363-74-9), with molecular formula C22H22N2O4S and molecular weight 410.13 g/mol. IUPAC: 3-(1-benzofuran-2-carbonyl)-1-[3-(dimethylamino)propyl]-4-hydroxy-2-thiophen-2-yl-2H-pyrrol-5-one.
Chemical Property Profile of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione
Property Insights of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione
The XLogP value of 4.0243 indicates that (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.99 Ų falls within the moderate polarity range, balancing permeability and solubility for (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione. Following Lipinski's Rule of Five, (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione?
The CAS number of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione is 618363-74-9.
What is the molecular formula of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione?
The molecular formula of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione is C22H22N2O4S.
What is the molecular weight of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione?
The molecular weight of (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione is 410.13 g/mol.
Where can I buy (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione?
You can request a quote for (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione?
Yes, KEHONG BIO provides custom synthesis services for (4E)-4-[1-benzofuran-2-yl(hydroxy)methylidene]-1-[3-(dimethylamino)propyl]-5-(thiophen-2-yl)pyrrolidine-2,3-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.