1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine
TL;DR: 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine (CAS 618098-30-9) is a chemical compound with molecular formula C15H11ClFN3 and molecular weight 287.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(3-chlorophenyl)-3-(4-fluorophenyl)pyrazol-5-amine
Also Known As: 1-(3-CHLOROPHENYL)-3-(4-FLUOROPHENYL)-1H-PYRAZOL-5-AMINE, 2-(3-chlorophenyl)-5-(4-fluorophenyl)pyrazol-3-amine, 5-Amino-1-(3-chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazole, 651-392-0, RefChem:423655
| Molecular Formula | C15H11ClFN3 |
|---|---|
| Molecular Weight | 287.06 g/mol |
| LogP | 3.914 |
| Topological Polar Surface Area | 43.84 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 287.06256 |
| Heavy Atoms | 20 |
| Complexity | 750.0651 |
Chemical Identifiers
| CAS Number | 618098-30-9 |
|---|---|
| SMILES | C1=CC(=CC(=C1)Cl)N2C(=CC(=N2)C3=CC=C(C=C3)F)N |
Product Overview
1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine (CAS 618098-30-9), with molecular formula C15H11ClFN3 and molecular weight 287.06 g/mol. IUPAC: 1-(3-chlorophenyl)-3-(4-fluorophenyl)pyrazol-5-amine.
Chemical Property Profile of 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine
Property Insights of 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine
The XLogP value of 3.914 indicates that 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.84 Ų, 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine?
The CAS number of 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine is 618098-30-9.
What is the molecular formula of 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine?
The molecular formula of 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine is C15H11ClFN3.
What is the molecular weight of 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine?
The molecular weight of 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine is 287.06 g/mol.
Where can I buy 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine?
You can request a quote for 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine?
Yes, KEHONG BIO provides custom synthesis services for 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-5-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.