4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one
TL;DR: 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one (CAS 618073-54-4) is a chemical compound with molecular formula C22H19F2NO4 and molecular weight 399.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-5-(2-fluorophenyl)-4-[(4-fluorophenyl)-hydroxymethylidene]-1-(oxolan-2-ylmethyl)pyrrolidine-2,3-dione
Also Known As: 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one, (4E)-5-(2-fluorophenyl)-4-[(4-fluorophenyl)-hydroxymethylidene]-1-(oxolan-2-ylmethyl)pyrrolidine-2,3-dione, 4-(4-FLUOROBENZOYL)-5-(2-FLUOROPHENYL)-3-HYDROXY-1-(TETRAHYDRO-2-FURANYLMETHYL)-1,5-DIHYDRO-2H-PYRROL-2-ONE, 4-(4-fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-[(oxolan-2-yl)methyl]-2,5-dihydro-1H-pyrrol-2-one, 4-(4-fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-(tetrahydro-2-furanylmethyl)-1
| Molecular Formula | C22H19F2NO4 |
|---|---|
| Molecular Weight | 399.13 g/mol |
| LogP | 3.5655 |
| Topological Polar Surface Area | 66.84 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 399.1282 |
| Heavy Atoms | 29 |
| Complexity | 980.5617 |
Chemical Identifiers
| CAS Number | 618073-54-4 |
|---|---|
| SMILES | C1CC(OC1)CN2C(/C(=C(/C3=CC=C(C=C3)F)\O)/C(=O)C2=O)C4=CC=CC=C4F |
Product Overview
4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one (CAS 618073-54-4), with molecular formula C22H19F2NO4 and molecular weight 399.13 g/mol. IUPAC: (4E)-5-(2-fluorophenyl)-4-[(4-fluorophenyl)-hydroxymethylidene]-1-(oxolan-2-ylmethyl)pyrrolidine-2,3-dione.
Chemical Property Profile of 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one
Property Insights of 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one
The XLogP value of 3.5655 indicates that 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.84 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one. Following Lipinski's Rule of Five, 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one?
The CAS number of 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one is 618073-54-4.
What is the molecular formula of 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one?
The molecular formula of 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one is C22H19F2NO4.
What is the molecular weight of 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one?
The molecular weight of 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one is 399.13 g/mol.
Where can I buy 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one?
You can request a quote for 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-Fluorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.