RefChem:404291
TL;DR: RefChem:404291 (CAS 618073-49-7) is a chemical compound with molecular formula C20H15Cl2N3O2S and molecular weight 431.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[(2,4-dichlorophenyl)methylidene]-2-(4-propan-2-yloxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
Also Known As: SALOR-INT L423165-1EA, (5E)-5-(2,4-dichlorobenzylidene)-2-(4-isopropoxyphenyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one, AF-399/41899544, 5-(2,4-Dichlorobenzylidene)-2-(4-isopropoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one, (5E)-5-[(2,4-dichlorophenyl)methylidene]-2-(4-propan-2-yloxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
| Molecular Formula | C20H15Cl2N3O2S |
|---|---|
| Molecular Weight | 431.03 g/mol |
| LogP | 4.4597 |
| Topological Polar Surface Area | 56.49 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 431.0262 |
| Heavy Atoms | 28 |
| Complexity | 1263.3309 |
Chemical Identifiers
| CAS Number | 618073-49-7 |
|---|---|
| SMILES | CC(C)OC1=CC=C(C=C1)C2=NN3C(=O)/C(=C\C4=C(C=C(C=C4)Cl)Cl)/SC3=N2 |
Product Overview
RefChem:404291 (CAS 618073-49-7), with molecular formula C20H15Cl2N3O2S and molecular weight 431.03 g/mol. IUPAC: (5E)-5-[(2,4-dichlorophenyl)methylidene]-2-(4-propan-2-yloxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one.
Chemical Property Profile of RefChem:404291
Property Insights of RefChem:404291
The XLogP value of 4.4597 indicates that RefChem:404291 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.49 Ų, RefChem:404291 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:404291 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:404291?
The CAS number of RefChem:404291 is 618073-49-7.
What is the molecular formula of RefChem:404291?
The molecular formula of RefChem:404291 is C20H15Cl2N3O2S.
What is the molecular weight of RefChem:404291?
The molecular weight of RefChem:404291 is 431.03 g/mol.
Where can I buy RefChem:404291?
You can request a quote for RefChem:404291 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:404291?
Yes, KEHONG BIO provides custom synthesis services for RefChem:404291 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.